2MPZ

Atomic model of the Abeta D23N "Iowa" mutant using solid-state NMR, EM and Rosetta modeling

Summary for 2MPZ

• Entry DOI: 10.2210/pdb2mpz/pdb
• NMR Information: BMRB: 25004
• Descriptor: Amyloid beta A4 protein (1 entity in total)
• Functional Keywords: amyloid, polymorhpism, sparse data, hybrid methods, protein fibril
• Biological source: Homo sapiens (human)
• Cellular location: Membrane; Single-pass type I membrane protein: P05067
• Total number of polymer chains: 27
• Total formula weight: 71553.89

Authors

Sgourakis, N.G.,Qiang, W. (deposition date: 2014-06-10, release date: 2015-04-22)

• Primary citation: Sgourakis, N.G.,Yau, W.M.,Qiang, W.; Modeling an in-register, parallel "iowa" a beta fibril structure using solid-state NMR data from labeled samples with rosetta.; Structure, 23:216-227, 2015; PubMed: 25543257; DOI: 10.1016/j.str.2014.10.022

Experimental method

SOLID-STATE NMR