2MPZ
Atomic model of the Abeta D23N "Iowa" mutant using solid-state NMR, EM and Rosetta modeling
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| a | 0016020 | cellular_component | membrane |
| A | 0016020 | cellular_component | membrane |
| B | 0016020 | cellular_component | membrane |
| C | 0016020 | cellular_component | membrane |
| D | 0016020 | cellular_component | membrane |
| E | 0016020 | cellular_component | membrane |
| F | 0016020 | cellular_component | membrane |
| G | 0016020 | cellular_component | membrane |
| H | 0016020 | cellular_component | membrane |
| I | 0016020 | cellular_component | membrane |
| J | 0016020 | cellular_component | membrane |
| K | 0016020 | cellular_component | membrane |
| L | 0016020 | cellular_component | membrane |
| M | 0016020 | cellular_component | membrane |
| N | 0016020 | cellular_component | membrane |
| O | 0016020 | cellular_component | membrane |
| P | 0016020 | cellular_component | membrane |
| Q | 0016020 | cellular_component | membrane |
| R | 0016020 | cellular_component | membrane |
| S | 0016020 | cellular_component | membrane |
| T | 0016020 | cellular_component | membrane |
| U | 0016020 | cellular_component | membrane |
| V | 0016020 | cellular_component | membrane |
| W | 0016020 | cellular_component | membrane |
| X | 0016020 | cellular_component | membrane |
| Y | 0016020 | cellular_component | membrane |
| Z | 0016020 | cellular_component | membrane |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 27 |
| Details | SITE: Cleavage; by alpha-secretase => ECO:0000305|PubMed:11851430 |
| Chain | Residue | Details |
| A | LYS16 | |
| J | LYS16 | |
| K | LYS16 | |
| L | LYS16 | |
| M | LYS16 | |
| N | LYS16 | |
| O | LYS16 | |
| P | LYS16 | |
| Q | LYS16 | |
| R | LYS16 | |
| S | LYS16 | |
| B | LYS16 | |
| T | LYS16 | |
| U | LYS16 | |
| V | LYS16 | |
| W | LYS16 | |
| X | LYS16 | |
| Y | LYS16 | |
| Z | LYS16 | |
| a | LYS16 | |
| C | LYS16 | |
| D | LYS16 | |
| E | LYS16 | |
| F | LYS16 | |
| G | LYS16 | |
| H | LYS16 | |
| I | LYS16 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 27 |
| Details | SITE: Cleavage; by theta-secretase => ECO:0000269|PubMed:16816112 |
| Chain | Residue | Details |
| A | PHE19 | |
| J | PHE19 | |
| K | PHE19 | |
| L | PHE19 | |
| M | PHE19 | |
| N | PHE19 | |
| O | PHE19 | |
| P | PHE19 | |
| Q | PHE19 | |
| R | PHE19 | |
| S | PHE19 | |
| B | PHE19 | |
| T | PHE19 | |
| U | PHE19 | |
| V | PHE19 | |
| W | PHE19 | |
| X | PHE19 | |
| Y | PHE19 | |
| Z | PHE19 | |
| a | PHE19 | |
| C | PHE19 | |
| D | PHE19 | |
| E | PHE19 | |
| F | PHE19 | |
| G | PHE19 | |
| H | PHE19 | |
| I | PHE19 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 27 |
| Details | SITE: Implicated in free radical propagation => ECO:0000250 |
| Chain | Residue | Details |
| A | GLY33 | |
| J | GLY33 | |
| K | GLY33 | |
| L | GLY33 | |
| M | GLY33 | |
| N | GLY33 | |
| O | GLY33 | |
| P | GLY33 | |
| Q | GLY33 | |
| R | GLY33 | |
| S | GLY33 | |
| B | GLY33 | |
| T | GLY33 | |
| U | GLY33 | |
| V | GLY33 | |
| W | GLY33 | |
| X | GLY33 | |
| Y | GLY33 | |
| Z | GLY33 | |
| a | GLY33 | |
| C | GLY33 | |
| D | GLY33 | |
| E | GLY33 | |
| F | GLY33 | |
| G | GLY33 | |
| H | GLY33 | |
| I | GLY33 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 27 |
| Details | SITE: Susceptible to oxidation => ECO:0000269|PubMed:10535332 |
| Chain | Residue | Details |
| A | MET35 | |
| J | MET35 | |
| K | MET35 | |
| L | MET35 | |
| M | MET35 | |
| N | MET35 | |
| O | MET35 | |
| P | MET35 | |
| Q | MET35 | |
| R | MET35 | |
| S | MET35 | |
| B | MET35 | |
| T | MET35 | |
| U | MET35 | |
| V | MET35 | |
| W | MET35 | |
| X | MET35 | |
| Y | MET35 | |
| Z | MET35 | |
| a | MET35 | |
| C | MET35 | |
| D | MET35 | |
| E | MET35 | |
| F | MET35 | |
| G | MET35 | |
| H | MET35 | |
| I | MET35 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 27 |
| Details | SITE: Cleavage; by gamma-secretase; site 1 => ECO:0000305|PubMed:11851430 |
| Chain | Residue | Details |
| A | VAL40 | |
| J | VAL40 | |
| K | VAL40 | |
| L | VAL40 | |
| M | VAL40 | |
| N | VAL40 | |
| O | VAL40 | |
| P | VAL40 | |
| Q | VAL40 | |
| R | VAL40 | |
| S | VAL40 | |
| B | VAL40 | |
| T | VAL40 | |
| U | VAL40 | |
| V | VAL40 | |
| W | VAL40 | |
| X | VAL40 | |
| Y | VAL40 | |
| Z | VAL40 | |
| a | VAL40 | |
| C | VAL40 | |
| D | VAL40 | |
| E | VAL40 | |
| F | VAL40 | |
| G | VAL40 | |
| H | VAL40 | |
| I | VAL40 |
