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8S4G
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BU of 8s4g by Molmil
Cryo-EM structure of the Anaphase-promoting complex/cyclosome (APC/C) bound to co-activator Cdh1 at 3.2 Angstrom resolution
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Hoefler, A, Yu, J, Chang, L, Zhang, Z, Yang, J, Boland, A, Barford, D.
登録日2024-02-21
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献New structural features of the APC/C revealed by high resolution cryo-EM structures of apo-APC/C and the APC/C-CDH1-EMI1 complex
To Be Published
8PKP
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BU of 8pkp by Molmil
Cryo-EM structure of the apo Anaphase-promoting complex/cyclosome (APC/C) at 3.2 Angstrom resolution
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Hoefler, A, Yu, J, Chang, L, Zhang, Z, Yang, J, Boland, A, Barford, D.
登録日2023-06-27
公開日2023-07-19
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献High-resolution structure of the Anaphase-promoting complex (APC/C) bound to co-activator Cdh1
To Be Published
8TAR
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BU of 8tar by Molmil
APC/C-CDH1-UBE2C-Ubiquitin-CyclinB-NTD
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Bodrug, T, Welsh, K.A, Bolhuis, D.L, Paulakonis, E, Martinez-Chacin, R.C, Liu, B, Pinkin, N, Bonacci, T, Cui, L, Xu, P, Roscow, O, Amann, S.J, Grishkovskaya, I, Emanuele, M.J, Harrison, J.S, Steimel, J.P, Hahn, K.M, Zhang, W, Zhong, E, Haselbach, D, Brown, N.G.
登録日2023-06-27
公開日2023-09-27
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C).
Nat.Struct.Mol.Biol., 30, 2023
8TAU
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BU of 8tau by Molmil
APC/C-CDH1-UBE2C-UBE2S-Ubiquitin-CyclinB
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Bodrug, T, Welsh, K.A, Bolhuis, D.L, Paulakonis, E, Martinez-Chacin, R.C, Liu, B, Pinkin, N, Bonacci, T, Cui, L, Xu, P, Roscow, O, Amann, S.J, Grishkovskaya, I, Emanuele, M.J, Harrison, J.S, Steimel, J.P, Hahn, K.M, Zhang, W, Zhong, E, Haselbach, D, Brown, N.G.
登録日2023-06-27
公開日2023-09-27
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C).
Nat.Struct.Mol.Biol., 30, 2023
8GFT
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BU of 8gft by Molmil
Hsp90 provides platform for CRaf dephosphorylation by PP5
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, ...
著者Jaime-Garza, M, Nowotny, C.A, Coutandin, D, Wang, F, Tabios, M, Agard, D.A.
登録日2023-03-08
公開日2023-05-03
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Hsp90 provides a platform for kinase dephosphorylation by PP5.
Nat Commun, 14, 2023
8GAE
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BU of 8gae by Molmil
Hsp90 provides platform for CRaf dephosphorylation by PP5
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, ...
著者Jaime-Garza, M, Nowotny, C.A, Coutandin, D, Wang, F, Tabios, M, Agard, D.A.
登録日2023-02-22
公開日2023-04-26
最終更新日2023-05-03
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Hsp90 provides a platform for kinase dephosphorylation by PP5.
Nat Commun, 14, 2023
8FFW
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BU of 8ffw by Molmil
Cryo-EM structure of the GR-Hsp90-FKBP51 complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ...
著者Noddings, C.M, Agard, D.A.
登録日2022-12-10
公開日2023-11-01
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor.
Nat.Struct.Mol.Biol., 30, 2023
8FFV
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BU of 8ffv by Molmil
Cryo-EM structure of the GR-Hsp90-FKBP52 complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ...
著者Noddings, C.M, Agard, D.A.
登録日2022-12-10
公開日2023-11-01
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor.
Nat.Struct.Mol.Biol., 30, 2023
8EBF
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BU of 8ebf by Molmil
C-terminal (TPR) domain of LIC11990 from Leptospira interrogans
分子名称: ACETATE ION, Cytoplasmic membrane protein, GLYCEROL
著者Larrieux, N, Buschiazzo, A.
登録日2022-08-31
公開日2022-09-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and function of a novel membrane-associated protein from Leptospira interrogans (gene LIC11990)
To Be Published
8DTG
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BU of 8dtg by Molmil
Cryo-EM structure of Arabidopsis SPY alternative conformation 1
分子名称: Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY
著者Kumar, S, Zhou, Y, Dillard, L, Borgnia, M.J, Bartesaghi, A, Zhou, P.
登録日2022-07-25
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structure of the full length Arabidopsis SPY with complete TPRs
Nat Commun, 2023
8DTI
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BU of 8dti by Molmil
Cryo-EM structure of Arabidopsis SPY in complex with GDP-fucose
分子名称: GUANOSINE-5'-DIPHOSPHATE-BETA-L-FUCOPYRANOSE, Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY
著者Kumar, S, Zhou, Y, Dillard, L, Borgnia, M.J, Bartesaghi, A, Zhou, P.
登録日2022-07-25
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM structure of the full length Arabidopsis SPY with complete TPRs
Nat Commun, 2023
8DTH
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BU of 8dth by Molmil
Cryo-EM structure of Arabidopsis SPY alternative conformation 2
分子名称: Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY
著者Kumar, S, Zhou, Y, Dillard, L, Borgnia, M.J, Bartesaghi, A, Zhou, P.
登録日2022-07-25
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structure of the full length Arabidopsis SPY with complete TPRs
Nat Commun, 2023
8DTF
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BU of 8dtf by Molmil
Cryo-EM structure of the full length Arabidopsis SPY with complete TPRs
分子名称: Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY
著者Kumar, S, Zhou, Y, Dillard, L, Borgnia, M.J, Bartesaghi, A, Zhou, P.
登録日2022-07-25
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structure of the full length Arabidopsis SPY with complete TPRs
Nat Commun, 2023
7YEH
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BU of 7yeh by Molmil
Cryo-EM structure of human OGT-OGA complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein O-GlcNAcase, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, ...
著者Lu, P, Liu, Y, Yu, H, Gao, H.
登録日2022-07-05
公開日2023-07-12
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex.
Nat Commun, 14, 2023
7YEA
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BU of 7yea by Molmil
Human O-GlcNAc transferase Dimer
分子名称: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
著者Gao, H, Lu, P, Liu, Y.
登録日2022-07-05
公開日2023-07-12
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (3.82 Å)
主引用文献Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex.
Nat Commun, 14, 2023
8A5Y
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BU of 8a5y by Molmil
S. cerevisiae apo unphosphorylated APC/C.
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ...
著者Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J.
登録日2022-06-16
公開日2022-08-31
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex and comparison to apo unphosphorylated and phosphorylated states
To Be Published
8A61
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BU of 8a61 by Molmil
S. cerevisiae apo phosphorylated APC/C
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ...
著者Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J.
登録日2022-06-16
公開日2022-08-31
実験手法ELECTRON MICROSCOPY (5.4 Å)
主引用文献Cryo-EM structure of the S. cerevisiae apo phosphorylated APC/C
To Be Published
7Y4I
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BU of 7y4i by Molmil
Crystal structure of SPINDLY in complex with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY
著者Xu, S.T, Wan, L.H.
登録日2022-06-14
公開日2022-12-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural insights into mechanism and specificity of the plant protein O-fucosyltransferase SPINDLY.
Nat Commun, 13, 2022
8A3T
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BU of 8a3t by Molmil
S. cerevisiae APC/C-Cdh1 complex
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ...
著者Barford, D, Vazquez-Fernandez, E, Zhang, Z, Yang, J.
登録日2022-06-09
公開日2022-08-31
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex
To Be Published
7ZR5
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BU of 7zr5 by Molmil
CryoEM structure of HSP90-CDC37-BRAF(V600E)-PP5(closed) complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ...
著者Oberoi, J, Pearl, L.H.
登録日2022-05-03
公開日2022-12-14
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation.
Nat Commun, 13, 2022
7ZR6
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BU of 7zr6 by Molmil
CryoEM structure of HSP90-CDC37-BRAF(V600E)-PP5(open) complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ...
著者Oberoi, J, Pearl, L.H.
登録日2022-05-03
公開日2022-12-28
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation.
Nat Commun, 13, 2022
7QE7
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BU of 7qe7 by Molmil
High-resolution structure of the Anaphase-promoting complex/cyclosome (APC/C) bound to co-activator Cdh1
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Hoefler, A, Yu, J, Chang, L, Zhang, Z, Yang, J, Boland, A, Barford, D.
登録日2021-12-01
公開日2022-01-26
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献High-resolution structure of the Anaphase-promoting complex (APC/C) bound to co-activator Cdh1
To Be Published
7OBE
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BU of 7obe by Molmil
X-ray structure of the phosphatase PAPP5 from Arabidopsis thaliana
分子名称: CHLORIDE ION, Isoform 2 of Serine/threonine-protein phosphatase 5, MANGANESE (II) ION
著者von Horsten, S, Essen, L.-O.
登録日2021-04-22
公開日2021-06-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Conformational Change of Tetratricopeptide Repeats Region Triggers Activation of Phytochrome-Associated Protein Phosphatase 5.
Front Plant Sci, 12, 2021
7NTF
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BU of 7ntf by Molmil
Cryo-EM structure of unliganded O-GlcNAc transferase
分子名称: Isoform 1 of UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
著者Meek, R.W, Blaza, J.N, Davies, G.J.
登録日2021-03-09
公開日2021-11-17
最終更新日2021-11-24
実験手法ELECTRON MICROSCOPY (5.32 Å)
主引用文献Cryo-EM structure provides insights into the dimer arrangement of the O-linked beta-N-acetylglucosamine transferase OGT.
Nat Commun, 12, 2021
7L7I
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BU of 7l7i by Molmil
Cryo-EM structure of Hsp90:FKBP51:p23 closed-state complex
分子名称: Heat shock protein HSP 90-alpha, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Peptidyl-prolyl cis-trans isomerase FKBP5, ...
著者Lee, K, Thwin, A.C, Tse, E, Gates, S.N, Southworth, D.R.
登録日2020-12-28
公開日2021-08-25
最終更新日2021-09-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献The structure of an Hsp90-immunophilin complex reveals cochaperone recognition of the client maturation state.
Mol.Cell, 81, 2021

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件を2024-05-01に公開中

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