8TAR

APC/C-CDH1-UBE2C-Ubiquitin-CyclinB-NTD

Summary for 8TAR

Entry DOI	10.2210/pdb8tar/pdb
EMDB information	41140
Descriptor	Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 13, ... (18 entities in total)
Functional Keywords	e3 ring ligase, ubiquitin ligase, ligase, transferase
Biological source	Homo sapiens (human) More
Total number of polymer chains	22
Total formula weight	1228921.53
Authors	Bodrug, T.,Welsh, K.A.,Bolhuis, D.L.,Paulakonis, E.,Martinez-Chacin, R.C.,Liu, B.,Pinkin, N.,Bonacci, T.,Cui, L.,Xu, P.,Roscow, O.,Amann, S.J.,Grishkovskaya, I.,Emanuele, M.J.,Harrison, J.S.,Steimel, J.P.,Hahn, K.M.,Zhang, W.,Zhong, E.,Haselbach, D.,Brown, N.G. (deposition date: 2023-06-27, release date: 2023-09-27, Last modification date: 2023-11-22)
Primary citation	Bodrug, T.,Welsh, K.A.,Bolhuis, D.L.,Paulаkonis, E.,Martinez-Chacin, R.C.,Liu, B.,Pinkin, N.,Bonacci, T.,Cui, L.,Xu, P.,Roscow, O.,Amann, S.J.,Grishkovskaya, I.,Emanuele, M.J.,Harrison, J.S.,Steimel, J.P.,Hahn, K.M.,Zhang, W.,Zhong, E.D.,Haselbach, D.,Brown, N.G. Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C). Nat.Struct.Mol.Biol., 30:1663-1674, 2023 Cited by PubMed: 37735619 DOI: 10.1038/s41594-023-01105-5 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4 Å)

Structure validation