7ZR5
CryoEM structure of HSP90-CDC37-BRAF(V600E)-PP5(closed) complex
Summary for 7ZR5
Entry DOI | 10.2210/pdb7zr5/pdb |
EMDB information | 14883 |
Descriptor | Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, Serine/threonine-protein kinase B-raf, ... (5 entities in total) |
Functional Keywords | complex, protein binding |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 367270.01 |
Authors | Oberoi, J.,Pearl, L.H. (deposition date: 2022-05-03, release date: 2022-12-14, Last modification date: 2022-12-21) |
Primary citation | Oberoi, J.,Guiu, X.A.,Outwin, E.A.,Schellenberger, P.,Roumeliotis, T.I.,Choudhary, J.S.,Pearl, L.H. HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation. Nat Commun, 13:7343-7343, 2022 Cited by PubMed: 36446791DOI: 10.1038/s41467-022-35143-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.9 Å) |
Structure validation
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