8GFT

Hsp90 provides platform for CRaf dephosphorylation by PP5

Summary for 8GFT

• Entry DOI: 10.2210/pdb8gft/pdb
• Related: 8GAE
• EMDB information: 29949 29957 29973 29976 29984
• Descriptor: Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, N-terminally processed, RAF proto-oncogene serine/threonine-protein kinase, ... (9 entities in total)
• Functional Keywords: chaperone, kinase, phosphatase, complex
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 305825.15

Authors

Jaime-Garza, M.,Nowotny, C.A.,Coutandin, D.,Wang, F.,Tabios, M.,Agard, D.A. (deposition date: 2023-03-08, release date: 2023-05-03)

• Primary citation: Jaime-Garza, M.,Nowotny, C.A.,Coutandin, D.,Wang, F.,Tabios, M.,Agard, D.A.; Hsp90 provides a platform for kinase dephosphorylation by PP5.; Nat Commun, 14:2197-2197, 2023; PubMed: 37069154; DOI: 10.1038/s41467-023-37659-7

Experimental method

ELECTRON MICROSCOPY (3.8 Å)