7YEH

Cryo-EM structure of human OGT-OGA complex

Summary for 7YEH

Entry DOI	10.2210/pdb7yeh/pdb
EMDB information	33773
Descriptor	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, Protein O-GlcNAcase, URIDINE-5'-DIPHOSPHATE, ... (4 entities in total)
Functional Keywords	o-glcnac transferase, o-glcnacase, complex, mutual inhibition, transferase, transferase-hydrolase complex, transferase/hydrolase
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	442574.01
Authors	Lu, P.,Liu, Y.,Yu, H.,Gao, H. (deposition date: 2022-07-05, release date: 2023-07-12, Last modification date: 2024-01-24)
Primary citation	Lu, P.,Liu, Y.,He, M.,Cao, T.,Yang, M.,Qi, S.,Yu, H.,Gao, H. Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex. Nat Commun, 14:6952-6952, 2023 Cited by PubMed: 37907462 DOI: 10.1038/s41467-023-42427-8 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.92 Å)

Structure validation