7ZR6

CryoEM structure of HSP90-CDC37-BRAF(V600E)-PP5(open) complex

Summary for 7ZR6

• Entry DOI: 10.2210/pdb7zr6/pdb
• EMDB information: 14884
• Descriptor: Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, Serine/threonine-protein kinase B-raf, ... (5 entities in total)
• Functional Keywords: complex, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 367270.01

Authors

Oberoi, J.,Pearl, L.H. (deposition date: 2022-05-03, release date: 2022-12-28)

• Primary citation: Oberoi, J.,Guiu, X.A.,Outwin, E.A.,Schellenberger, P.,Roumeliotis, T.I.,Choudhary, J.S.,Pearl, L.H.; HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation.; Nat Commun, 13:7343-7343, 2022; PubMed: 36446791; DOI: 10.1038/s41467-022-35143-2

Experimental method

ELECTRON MICROSCOPY (4.2 Å)