7L7I

Cryo-EM structure of Hsp90:FKBP51:p23 closed-state complex

Summary for 7L7I

• Entry DOI: 10.2210/pdb7l7i/pdb
• Related: 7L7J
• EMDB information: 23213 23214
• Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP5, Heat shock protein HSP 90-alpha, Prostaglandin E synthase 3, ... (4 entities in total)
• Functional Keywords: isomerase-chaperone complex, isomerase/chaperone
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 240586.43

Authors

Lee, K.,Thwin, A.C.,Tse, E.,Gates, S.N.,Southworth, D.R. (deposition date: 2020-12-28, release date: 2021-08-25, Last modification date: 2021-09-15)

• Primary citation: Lee, K.,Thwin, A.C.,Nadel, C.M.,Tse, E.,Gates, S.N.,Gestwicki, J.E.,Southworth, D.R.; The structure of an Hsp90-immunophilin complex reveals cochaperone recognition of the client maturation state.; Mol.Cell, 81:3496-, 2021; PubMed: 34380015; DOI: 10.1016/j.molcel.2021.07.023

Experimental method

ELECTRON MICROSCOPY (3.3 Å)