7L7I
Cryo-EM structure of Hsp90:FKBP51:p23 closed-state complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | C | Peptidyl-prolyl cis-trans isomerase FKBP5 | polymer | 457 | 51290.2 | 1 | UniProt (Q13451) Pfam (PF00254) Pfam (PF00515) In PDB | Homo sapiens (Human) | PPIase FKBP5,51 kDa FK506-binding protein,FKBP-51,54 kDa progesterone receptor-associated immunophilin,Androgen-regulated protein 6,FF1 antigen,FK506-binding protein 5,FKBP-5,FKBP54,p54,HSP90-binding immunophilin,Rotamase |
| 2 | A, B | Heat shock protein HSP 90-alpha | polymer | 732 | 84781.7 | 2 | UniProt (P07900) Pfam (PF13589) Pfam (PF00183) In PDB | Homo sapiens (Human) | Heat shock 86 kDa,HSP86,Lipopolysaccharide-associated protein 2,LPS-associated protein 2,Renal carcinoma antigen NY-REN-38 |
| 3 | E | Prostaglandin E synthase 3 | polymer | 160 | 18720.4 | 1 | UniProt (Q15185) Pfam (PF04969) In PDB | Homo sapiens (Human) | Cytosolic prostaglandin E2 synthase,cPGES,Hsp90 co-chaperone,Progesterone receptor complex p23,Telomerase-binding protein p23 |
| 4 | A, B | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 239574.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1012.4 | |
| All* | Total formula weight | 240586.4 |
