PDB: 435 件ウェブページステータス検索Chemie searchBIRD

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3FQ9	Design of an insulin analog with enhanced receptor-binding selectivity. Rationale, structure, and therapeutic implications 分子名称: Insulin, ZINC ION 著者 Zhao, M, Wan, Z.L, Whittaker, L, Xu, B, Phillips, N, Katsoyannis, P, Whittaker, J, Weiss, M.A. 登録日 2009-01-07 公開日 2009-08-04 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Design of an insulin analog with enhanced receptor binding selectivity: rationale, structure, and therapeutic implications. J.Biol.Chem., 284, 2009
3AIY	R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, REFINED AVERAGE STRUCTURE 分子名称: PHENOL, PROTEIN (INSULIN) 著者 O'Donoghue, S.I, Chang, X, Abseher, R, Nilges, M, Led, J.J. 登録日 1998-12-29 公開日 2000-02-28 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Unraveling the symmetry ambiguity in a hexamer: calculation of the R6 human insulin structure. J.Biomol.NMR, 16, 2000
3GF1	SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR 1: A NUCLEAR MAGNETIC RESONANCE AND RESTRAINED MOLECULAR DYNAMICS STUDY 分子名称: INSULIN-LIKE GROWTH FACTOR I 著者 Cooke, R.M, Harvey, T.S, Campbell, I.D. 登録日 1991-01-24 公開日 1993-04-15 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study. Biochemistry, 30, 1991
3GKY	The Structural Basis of an ER Stress-Associated Bottleneck in a Protein Folding Landscape 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Liu, M, Wan, Z.L, Chu, Y.C, Alddin, H, Klaproth, B, Weiss, M.A. 登録日 2009-03-11 公開日 2009-03-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of a "nonfoldable" insulin: IMPAIRED FOLDING EFFICIENCY DESPITE NATIVE ACTIVITY. J.Biol.Chem., 284, 2009
5L3N	D11 bound [N29, S39_PQ]-IGF-II 分子名称: Insulin-like growth factor II 著者 Hexnerova, R. 登録日 2016-05-23 公開日 2016-08-10 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
5L3L	D11 bound IGF-II 分子名称: Insulin-like growth factor II 著者 Hexnerova, R. 登録日 2016-05-23 公開日 2016-08-10 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
5L3M	D11 bound [S39_PQ]-IGF-II 分子名称: Insulin-like growth factor II 著者 Hexnerova, R. 登録日 2016-05-23 公開日 2016-08-10 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
8HSF	Insulin triple mutant INS-RQD 分子名称: Insulin A chain, Insulin B chain 著者 Kundapura, S.V, Rao, S.S, Kulal, A, Ramagopal, U.A. 登録日 2022-12-19 公開日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Insulin triple mutant INS-RQD To Be Published
8HGZ	Crystal structure of insulin 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 DeMirci, H, Ayan, E. 登録日 2022-11-16 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Comparative Study of High-Resolution LysB29(N epsilon-myristoyl) des(B30) Insulin Structures Display Novel Dynamic Causal Interrelations in Monomeric-Dimeric Motions Crystals, 13, 2023
5LIS	Insulin solved by Native SAD from a dataset collected in one second 分子名称: Insulin 著者 Casanas, A, Finke, A, Wang, M. 登録日 2016-07-15 公開日 2016-08-03 最終更新日 2016-09-28 実験手法 X-RAY DIFFRACTION (2.293 Å) 主引用文献 EIGER detector: application in macromolecular crystallography. Acta Crystallogr D Struct Biol, 72, 2016
8IPZ	Crystal structure of insulin detemir 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 DeMirci, H, Ayan, E. 登録日 2023-03-15 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of insulin detemir To Be Published
3I40	Human insulin 分子名称: Insulin A chain, Insulin B chain 著者 Timofeev, V.I, Bezuglov, V.V, Miroshnikov, K.A, Chuprov-Netochin, R.N, Kuranova, I.P. 登録日 2009-07-01 公開日 2010-01-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 X-ray investigation of gene-engineered human insulin crystallized from a solution containing polysialic acid. Acta Crystallogr.,Sect.F, 66, 2010
3I3Z	Human insulin 分子名称: Insulin A chain, Insulin B chain 著者 Timofeev, V.I, Bezuglov, V.V, Miroshnikov, K.A, Cuprov-Netochin, R.N, Samigina, V.R, Kuranova, I.P. 登録日 2009-07-01 公開日 2010-01-05 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 X-ray investigation of gene-engineered human insulin crystallized from a solution containing polysialic acid. Acta Crystallogr.,Sect.F, 66, 2010
5MIZ	MD ensemble of bovine insulin 分子名称: Insulin 著者 Efimov, S.V, Zgadzay, Y.O, Klochkov, V.V. 登録日 2016-11-29 公開日 2017-01-25 最終更新日 2019-05-08 実験手法 SOLUTION NMR 主引用文献 MD ensemble of bovine insulin To Be Published
3INC	Crystal structure of human insulin with Ni+2 complex 分子名称: Insulin A chain, Insulin B chain, NICKEL (II) ION 著者 Raghavendra, N, Pattabhi, V, Rajan, S.S. 登録日 2009-08-12 公開日 2010-08-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Metal induced conformational changes in human insulin: Crystal structures of Sr+2, Ni+2 and Cu+2 complexes of human insulin To be Published
5MHD	Biosynthetic engineered A22S-B3K-B31R human insulin monomer structure in water/acetonitrile solutions. 分子名称: Insulin 著者 Bocian, W, Kozerski, L, Bednarek, E, Sitkowski, J. 登録日 2016-11-24 公開日 2017-08-09 最終更新日 2019-05-08 実験手法 SOLUTION NMR 主引用文献 Structure and pharmaceutical formulation development of a new long-acting recombinant human insulin analog studied by NMR and MS. J Pharm Biomed Anal, 135, 2017
3INS	STRUCTURE OF INSULIN. RESULTS OF JOINT NEUTRON AND X-RAY REFINEMENT 分子名称: INSULIN (CHAIN A), INSULIN (CHAIN B), ZINC ION 著者 Wlodawer, A, Savage, H. 登録日 1988-10-14 公開日 1989-01-09 最終更新日 2017-11-29 実験手法 NEUTRON DIFFRACTION (1.5 Å), X-RAY DIFFRACTION 主引用文献 Structure of insulin: results of joint neutron and X-ray refinement. Acta Crystallogr.,Sect.B, 45, 1989
3IR0	Crystal Structure of Human Insulin complexed with Cu+2 metal ion 分子名称: COPPER (II) ION, Insulin A chain, Insulin B chain 著者 Raghavendra, N, Pattabhi, V, Rajan, S.S. 登録日 2009-08-21 公開日 2010-09-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Metal induced structural changes observed in Human insulin To be Published
3ILG	Crystal structure of humnan insulin Sr+2 complex 分子名称: Insulin A chain, Insulin B chain, STRONTIUM ION 著者 Raghavendra, N, Pattabhi, V, Rajan, S.S. 登録日 2009-08-07 公開日 2010-08-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Metal induced conformational changes in human insulin: Crystal structures of Sr+2, Ni+2 and Cu+2 complexes of human insulin To be Published
5MAM	Human insulin in complex with serotonin 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. 登録日 2016-11-03 公開日 2017-04-05 最終更新日 2017-05-31 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules. J. Biol. Chem., 292, 2017
5MWQ	Biosynthetic engineered A21K-B31K-B32R human insulin monomer structure in water/acetonitrile solution 分子名称: Insulin 著者 Bocian, W, Kozerski, L. 登録日 2017-01-19 公開日 2018-02-14 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Lysine mis-incorporation at asparagine position during recombinant proteins production in E. coli To Be Published
5MT3	Human insulin in complex with serotonin and arginine 分子名称: ARGININE, CHLORIDE ION, Insulin, ... 著者 Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. 登録日 2017-01-06 公開日 2017-04-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules. J. Biol. Chem., 292, 2017
5MT9	Human insulin in complex with serotonin and arginine 分子名称: ARGININE, CHLORIDE ION, Insulin, ... 著者 Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. 登録日 2017-01-07 公開日 2017-04-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules. J. Biol. Chem., 292, 2017
8ONK	Human insulin in complex with the analytical antibody S1 Fab and the analytical antibody HUI-001 Fab 分子名称: Heavy chain of analytical antibody HUI-001 Fab, Heavy chain of analytical antibody S1 Fab, Insulin A chain, ... 著者 Johansson, E. 登録日 2023-04-03 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (3.403 Å) 主引用文献 Macromolecular structure of insulin and IgE clonality impacts IgE-mediated activation of sensitized basophils To Be Published
8ONI	Human insulin in complex with the analytical antibody S1 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of analytical antibody S1 Fab, Insulin A chain, ... 著者 Johansson, E. 登録日 2023-04-03 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Macromolecular structure of insulin and IgE clonality impacts IgE-mediated activation of sensitized basophils To Be Published

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