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5MHD

Biosynthetic engineered A22S-B3K-B31R human insulin monomer structure in water/acetonitrile solutions.

Summary for 5MHD
Entry DOI10.2210/pdb5mhd/pdb
NMR InformationBMRB: 34070
DescriptorInsulin (2 entities in total)
Functional Keywordshuman insulin, water/acetonitrile solution, mutant, hormone
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight6077.00
Authors
Bocian, W.,Kozerski, L.,Bednarek, E.,Sitkowski, J. (deposition date: 2016-11-24, release date: 2017-08-09, Last modification date: 2019-05-08)
Primary citationBednarek, E.,Sitkowski, J.,Bocian, W.,Borowicz, P.,Pucienniczak, G.,Stadnik, D.,Surmacz-Chwedoruk, W.,Jaworska, B.,Kozerski, L.
Structure and pharmaceutical formulation development of a new long-acting recombinant human insulin analog studied by NMR and MS.
J Pharm Biomed Anal, 135:126-132, 2017
Cited by
PubMed: 28024260
DOI: 10.1016/j.jpba.2016.12.005
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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