1PDG
 
 | | CRYSTAL STRUCTURE OF HUMAN PLATELET-DERIVED GROWTH FACTOR BB | | 分子名称: | PLATELET-DERIVED GROWTH FACTOR BB | | 著者 | Oefner, C, Darcy, A.D, Winkler, F.K, Eggimann, B, Hosnag, M. | | 登録日 | 1992-07-14 | | 公開日 | 1994-01-31 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of human platelet-derived growth factor BB.
EMBO J., 11, 1992
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1VPF
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2VPF
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1FLT
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1BJ1
 | | VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH A NEUTRALIZING ANTIBODY | | 分子名称: | Fab fragment, heavy chain, light chain, ... | | 著者 | Muller, Y.A, Christinger, H.W, De Vos, A.M. | | 登録日 | 1998-06-30 | | 公開日 | 1999-01-13 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 A resolution and mutational analysis of the interface.
Structure, 6, 1998
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1VPP
 | | COMPLEX BETWEEN VEGF AND A RECEPTOR BLOCKING PEPTIDE | | 分子名称: | PROTEIN (PEPTIDE V108), PROTEIN (VASCULAR ENDOTHELIAL GROWTH FACTOR) | | 著者 | Wiesmann, C, Christinger, H.W, Cochran, A.G, Cunningham, B.C, Fairbrother, W.J, Keenan, C.J, Meng, G, de Vos, A.M. | | 登録日 | 1998-10-09 | | 公開日 | 1999-02-23 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the complex between VEGF and a receptor-blocking peptide.
Biochemistry, 37, 1998
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1QTY
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1CZ8
 | | VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH AN AFFINITY MATURED ANTIBODY | | 分子名称: | HEAVY CHAIN OF NEUTRALIZING ANTIBODY, LIGHT CHAIN OF NEUTRALIZING ANTIBODY, SULFATE ION, ... | | 著者 | Chen, Y, Wiesmann, C, Fuh, G, Li, B, Christinger, H.W, McKay, P, de Vos, A.M, Lowman, H.B. | | 登録日 | 1999-09-01 | | 公開日 | 2000-03-20 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen.
J.Mol.Biol., 293, 1999
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1FZV
 | | THE CRYSTAL STRUCTURE OF HUMAN PLACENTA GROWTH FACTOR-1 (PLGF-1), AN ANGIOGENIC PROTEIN AT 2.0A RESOLUTION | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, PLACENTA GROWTH FACTOR | | 著者 | Iyer, S, Leonidas, D.D, Swaminathan, G.J, Maglione, D, Battisti, M, Tucci, M, Persico, M.G, Acharya, K.R. | | 登録日 | 2000-10-04 | | 公開日 | 2001-05-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The crystal structure of human placenta growth factor-1 (PlGF-1), an angiogenic protein, at 2.0 A resolution.
J.Biol.Chem., 276, 2001
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1KAT
 | | Solution Structure of a Phage-Derived Peptide Antagonist in Complex with Vascular Endothelial Growth Factor | | 分子名称: | Phage-Derived Peptide Antagonist, Vascular Endothelial Growth Factor | | 著者 | Pan, B, Li, B, Russell, S.J, Tom, J.Y.K, Cochran, A.G, Fairbrother, W.J. | | 登録日 | 2001-11-02 | | 公開日 | 2002-11-02 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of a Phage-derived Peptide Antagonist in Complex with Vascular Endothelial Growth Factor
J.Mol.Biol., 316, 2002
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1MJV
 | | DISULFIDE DEFICIENT MUTANT OF VASCULAR ENDOTHELIAL GROWTH FACTOR A (C51A and C60A) | | 分子名称: | Vascular Endothelial Growth Factor A | | 著者 | Muller, Y.A, Heiring, C, Misselwitz, R, Welfle, K, Welfle, H. | | 登録日 | 2002-08-28 | | 公開日 | 2002-12-11 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor
J.Biol.Chem., 277, 2002
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1MKG
 | | DISULFIDE DEFICIENT MUTANT OF VASCULAR ENDOTHELIAL GROWTH FACTOR A (C57A and C102A) | | 分子名称: | Vascular Endothelial Growth Factor A | | 著者 | Muller, Y.A, Heiring, C, Misselwitz, R, Welfle, K, Welfle, H. | | 登録日 | 2002-08-29 | | 公開日 | 2002-12-11 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor
J.Biol.Chem., 277, 2002
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1MKK
 | | Disulfide deficient mutant of vascular endothelial growth factor A (C61A and C104A) | | 分子名称: | Vascular Endothelial Growth Factor A | | 著者 | Muller, Y.A, Heiring, C, Misselwitz, R, Welfle, K, Welfle, H. | | 登録日 | 2002-08-29 | | 公開日 | 2002-12-11 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | | 主引用文献 | The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor
J.Biol.Chem., 277, 2002
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1RV6
 | | Crystal Structure of PlGF in Complex with Domain 2 of VEGFR1 | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FLT1 protein, placenta growth factor (PlGF) | | 著者 | Christinger, H.W, Fuh, G, de Vos, A.M, Wiesmann, C. | | 登録日 | 2003-12-12 | | 公開日 | 2004-01-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | The crystal structure of placental growth factor in complex with domain 2 of vascular endothelial growth factor receptor-1.
J.Biol.Chem., 279, 2004
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1TZH
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1TZI
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1WQ8
 | | Crystal structure of Vammin, a VEGF-F from a snake venom | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Vascular endothelial growth factor toxin | | 著者 | Suto, K, Yamazaki, Y, Morita, T, Mizuno, H. | | 登録日 | 2004-09-23 | | 公開日 | 2004-12-07 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structures of novel vascular endothelial growth factors (VEGF) from snake venoms: insight into selective VEGF binding to kinase insert domain-containing receptor but not to fms-like tyrosine kinase-1.
J.Biol.Chem., 280, 2005
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1WQ9
 | | Crystal structure of VR-1, a VEGF-F from a snake venom | | 分子名称: | Vascular endothelial growth factor | | 著者 | Suto, K, Yamazaki, Y, Morita, T, Mizuno, H. | | 登録日 | 2004-09-24 | | 公開日 | 2004-12-07 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures of novel vascular endothelial growth factors (VEGF) from snake venoms: insight into selective VEGF binding to kinase insert domain-containing receptor but not to fms-like tyrosine kinase-1.
J.Biol.Chem., 280, 2005
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2FJG
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2FJH
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2GNN
 | | Crystal Structure of the Orf Virus NZ2 Variant of VEGF-E | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, BENZAMIDINE, ... | | 著者 | Prota, A.E, Pieren, M, Wagner, A, Kostrewa, D, Winkler, F.K, Ballmer-Hofer, K. | | 登録日 | 2006-04-10 | | 公開日 | 2006-05-09 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the Orf virus NZ2 variant of vascular endothelial growth factor-E. Implications for receptor specificity.
J.Biol.Chem., 281, 2006
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2C7W
 | | Crystal Structure of human vascular endothelial growth factor-B: Identification of amino acids important for angiogeninc activity | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, VASCULAR ENDOTHELIAL GROWTH FACTOR B PRECURSOR | | 著者 | Iyer, S, Scotney, P.D, Nash, A.D, Acharya, K.R. | | 登録日 | 2005-11-29 | | 公開日 | 2007-01-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Crystal Structure of Human Vascular Endothelial Growth Factor-B: Identification of Amino Acids Important for Receptor Binding
J.Mol.Biol., 359, 2006
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2QR0
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2VWE
 | | Crystal Structure of Vascular Endothelial Growth Factor-B in Complex with a Neutralizing Antibody Fab Fragment | | 分子名称: | ANTI-VEGF-B MONOCLONAL ANTIBODY, VASCULAR ENDOTHELIAL GROWTH FACTOR B | | 著者 | Leonard, P, Scotney, P.D, Jabeen, T, Iyer, S, Fabri, L.J, Nash, A.D, Acharya, K.R. | | 登録日 | 2008-06-23 | | 公開日 | 2008-11-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Crystal Structure of Vascular Endothelial Growth Factor-B in Complex with a Neutralising Antibody Fab Fragment.
J.Mol.Biol., 384, 2008
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3BDY
 | | Dual specific bH1 Fab in complex with VEGF | | 分子名称: | Fab Fragment -Heavy Chain, Fab Fragment -Light Chain, GLYCEROL, ... | | 著者 | Bostrom, J.M, Wiesmann, C, Appleton, B.A. | | 登録日 | 2007-11-15 | | 公開日 | 2008-11-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Variants of the antibody herceptin that interact with HER2 and VEGF at the antigen binding site
Science, 323, 2009
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