1FZV

THE CRYSTAL STRUCTURE OF HUMAN PLACENTA GROWTH FACTOR-1 (PLGF-1), AN ANGIOGENIC PROTEIN AT 2.0A RESOLUTION

Summary for 1FZV
Related1FLT 2VPF
DescriptorPLACENTA GROWTH FACTOR, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total)
Functional Keywordscysteine-knot family, growth factor, angiogenesis, hormone-growth factor complex, hormone/growth factor
Biological sourceHomo sapiens (human)
Cellular locationSecreted: P49763
Total number of polymer chains2
Total formula weight29980.48
Authors
Iyer, S.,Leonidas, D.D.,Swaminathan, G.J.,Maglione, D.,Battisti, M.,Tucci, M.,Persico, M.G.,Acharya, K.R. (deposition date: 2000-10-04, release date: 2001-05-09, Last modification date: 2018-01-31)
Primary citationAcharya, K.R.,Battisti, M.,Iyer, S.,Leonidas, D.D.,Maglione, D.,Persico, M.G.,Swaminathan, G.J.,Tucci, M.
The crystal structure of human placenta growth factor-1 (PlGF-1), an angiogenic protein, at 2.0 A resolution.
J.Biol.Chem., 276:12153-12161, 2001
PubMed: 11069911
DOI: 110.1074/jbc.M008055200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation
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PDB entries from 2021-06-16