1MKG

DISULFIDE DEFICIENT MUTANT OF VASCULAR ENDOTHELIAL GROWTH FACTOR A (C57A and C102A)

Summary for 1MKG

Entry DOI	10.2210/pdb1mkg/pdb
Related	1MJV 1MKK 2VPF
Descriptor	Vascular Endothelial Growth Factor A (2 entities in total)
Functional Keywords	cystine-knot growth factor, hormone-growth factor complex, hormone/growth factor
Biological source	Homo sapiens (human)
Cellular location	Secreted : P15692
Total number of polymer chains	4
Total formula weight	44783.86
Authors	Muller, Y.A.,Heiring, C.,Misselwitz, R.,Welfle, K.,Welfle, H. (deposition date: 2002-08-29, release date: 2002-12-11, Last modification date: 2021-10-27)
Primary citation	Muller, Y.A.,Heiring, C.,Misselwitz, R.,Welfle, K.,Welfle, H. The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor J.Biol.Chem., 277:43410-43416, 2002 Cited by PubMed: 12207021 DOI: 10.1074/jbc.M206438200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation