1MKG
DISULFIDE DEFICIENT MUTANT OF VASCULAR ENDOTHELIAL GROWTH FACTOR A (C57A and C102A)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Vascular Endothelial Growth Factor A | polymer | 96 | 11196.0 | 4 | UniProt (P15692) Pfam (PF00341) | Homo sapiens (human) | VEGF-A, Vascular permeability factor, VPF |
| 2 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 134 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 14 - 108 (UniProt: P15692)
| PDB | External Database | Details |
|---|---|---|
| Met 13 | - | cloning artifact |
| Ala 57 | Cys 83 | engineered mutation |
| Ala 102 | Cys 128 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 44783.9 | |
| All* | Total formula weight | 44783.9 |
