1VPP
COMPLEX BETWEEN VEGF AND A RECEPTOR BLOCKING PEPTIDE
Summary for 1VPP
| Entry DOI | 10.2210/pdb1vpp/pdb |
| Descriptor | PROTEIN (VASCULAR ENDOTHELIAL GROWTH FACTOR), PROTEIN (PEPTIDE V108) (3 entities in total) |
| Functional Keywords | cystine knot, angiogenesis, vasculogenesis, receptor blocking peptide, growth factor-growth factor inhibitor complex, growth factor/growth factor inhibitor |
| Biological source | Homo sapiens (human) More |
| Cellular location | Secreted: P15692 |
| Total number of polymer chains | 4 |
| Total formula weight | 28414.34 |
| Authors | Wiesmann, C.,Christinger, H.W.,Cochran, A.G.,Cunningham, B.C.,Fairbrother, W.J.,Keenan, C.J.,Meng, G.,de Vos, A.M. (deposition date: 1998-10-09, release date: 1999-02-23, Last modification date: 2023-08-23) |
| Primary citation | Wiesmann, C.,Christinger, H.W.,Cochran, A.G.,Cunningham, B.C.,Fairbrother, W.J.,Keenan, C.J.,Meng, G.,de Vos, A.M. Crystal structure of the complex between VEGF and a receptor-blocking peptide. Biochemistry, 37:17765-17772, 1998 Cited by PubMed: 9922142DOI: 10.1021/bi9819327 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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