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1RV6

Crystal Structure of PlGF in Complex with Domain 2 of VEGFR1

Summary for 1RV6
Entry DOI10.2210/pdb1rv6/pdb
Descriptorplacenta growth factor (PlGF), FLT1 protein, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
Functional Keywordsplgf, vegf family, cystine knot, growth factor, ligand-receptor complex, specificity, hormone-growth factor-receptor complex, hormone/growth factor/receptor
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted: P49763
Isoform Flt1: Cell membrane; Single-pass type I membrane protein. Isoform sFlt1: Secreted: P17948
Total number of polymer chains4
Total formula weight46403.45
Authors
Christinger, H.W.,Fuh, G.,de Vos, A.M.,Wiesmann, C. (deposition date: 2003-12-12, release date: 2004-01-20, Last modification date: 2023-08-23)
Primary citationChristinger, H.W.,Fuh, G.,de Vos, A.M.,Wiesmann, C.
The crystal structure of placental growth factor in complex with domain 2 of vascular endothelial growth factor receptor-1.
J.Biol.Chem., 279:10382-10388, 2004
Cited by
PubMed: 14684734
DOI: 10.1074/jbc.M313237200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.45 Å)
Structure validation

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