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2QR0

Structure of VEGF complexed to a Fab containing TYR and SER in the CDRs

Summary for 2QR0
Entry DOI10.2210/pdb2qr0/pdb
DescriptorFab-Fragment Light Chain, Fab-Fragment Heavy Chain, Vascular endothelial growth factor A (3 entities in total)
Functional Keywordsvegf; antibody recognition; specificity; phage display, immune system
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted : P15692
Total number of polymer chains24
Total formula weight465857.59
Authors
Wiesmann, C. (deposition date: 2007-07-27, release date: 2007-08-14, Last modification date: 2017-10-25)
Primary citationFellouse, F.A.,Esaki, K.,Birtalan, S.,Raptis, D.,Cancasci, V.J.,Koide, A.,Jhurani, P.,Vasser, M.,Wiesmann, C.,Kossiakoff, A.A.,Koide, S.,Sidhu, S.S.
High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries
J.Mol.Biol., 373:924-940, 2007
Cited by
PubMed: 17825836
DOI: 10.1016/j.jmb.2007.08.005
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.5 Å)
Structure validation

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