2C7W

Crystal Structure of human vascular endothelial growth factor-B: Identification of amino acids important for angiogeninc activity

Summary for 2C7W

Entry DOI	10.2210/pdb2c7w/pdb
Descriptor	VASCULAR ENDOTHELIAL GROWTH FACTOR B PRECURSOR, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total)
Functional Keywords	vascular endothelial growth factor-b, angiogenesis, cysteine-knot motif, tyrosine kinase, ischemia, mitogen, glycoprotein, growth factor, heparin-binding
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Secreted: P49765
Total number of polymer chains	2
Total formula weight	22432.27
Authors	Iyer, S.,Scotney, P.D.,Nash, A.D.,Acharya, K.R. (deposition date: 2005-11-29, release date: 2007-01-30, Last modification date: 2023-12-13)
Primary citation	Iyer, S.,Scotney, P.D.,Nash, A.D.,Acharya, K.R. Crystal Structure of Human Vascular Endothelial Growth Factor-B: Identification of Amino Acids Important for Receptor Binding J.Mol.Biol., 359:76-, 2006 Cited by PubMed: 16616187 DOI: 10.1016/J.JMB.2006.03.002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.48 Å)

Structure validation