2C7W
Crystal Structure of human vascular endothelial growth factor-B: Identification of amino acids important for angiogeninc activity
Summary for 2C7W
Entry DOI | 10.2210/pdb2c7w/pdb |
Descriptor | VASCULAR ENDOTHELIAL GROWTH FACTOR B PRECURSOR, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total) |
Functional Keywords | vascular endothelial growth factor-b, angiogenesis, cysteine-knot motif, tyrosine kinase, ischemia, mitogen, glycoprotein, growth factor, heparin-binding |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Secreted: P49765 |
Total number of polymer chains | 2 |
Total formula weight | 22432.27 |
Authors | Iyer, S.,Scotney, P.D.,Nash, A.D.,Acharya, K.R. (deposition date: 2005-11-29, release date: 2007-01-30, Last modification date: 2023-12-13) |
Primary citation | Iyer, S.,Scotney, P.D.,Nash, A.D.,Acharya, K.R. Crystal Structure of Human Vascular Endothelial Growth Factor-B: Identification of Amino Acids Important for Receptor Binding J.Mol.Biol., 359:76-, 2006 Cited by PubMed: 16616187DOI: 10.1016/J.JMB.2006.03.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.48 Å) |
Structure validation
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