PDB: 5470 件ウェブページステータス検索Chemie searchBIRD

---

6OLI	Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC) 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-16 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OM0	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-17 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OLE	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-16 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
5WWF	Crystal structure of hnRNPA2B1 in complex with RNA 分子名称: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA 著者 Wu, B.X, Su, S.C, Ma, J.B. 登録日 2017-01-01 公開日 2018-01-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1. Nat Commun, 9, 2018
8Y0W	dormant ribosome with eIF5A, eEF2 and SERBP1 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Du, M, Zeng, F. 登録日 2024-01-23 公開日 2024-02-07 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 dormant ribosome with eIF5A, eEF2 and SERBP1 To Be Published
5WWE	Crystal structure of hnRNPA2B1 in complex with RNA 分子名称: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*GP*GP*GP*AP*CP*UP*AP*GP*A)-3') 著者 Wu, B.X, Su, S.C, Ma, J.B. 登録日 2017-01-01 公開日 2018-01-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1. Nat Commun, 9, 2018
5WWG	Crystal structure of hnRNPA2B1 in complex with AAGGACUUGC 分子名称: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*AP*GP*GP*AP*CP*UP*U)-3') 著者 Wu, B.X, Su, S.C, Ma, J.B. 登録日 2017-01-01 公開日 2018-01-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1. Nat Commun, 9, 2018
4FO9	Crystal structure of the E3 SUMO Ligase PIAS2 分子名称: E3 SUMO-protein ligase PIAS2, UNKNOWN ATOM OR ION, ZINC ION 著者 Dong, A, Hu, J, Dobrovetsky, E, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) 登録日 2012-06-20 公開日 2012-07-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Crystal structure of the E3 SUMO Ligase PIAS2 to be published
6AH0	The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Zhan, X, Yan, C, Zhang, X, Shi, Y. 登録日 2018-08-15 公開日 2018-11-14 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (5.7 Å) 主引用文献 Structures of the human pre-catalytic spliceosome and its precursor spliceosome. Cell Res., 28, 2018
6AHD	The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolution 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Brr2, U5 small nuclear ribonucleoprotein 200 kDa helicase, ... 著者 Zhan, X, Yan, C, Zhang, X, Shi, Y. 登録日 2018-08-17 公開日 2018-11-14 最終更新日 2021-06-30 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structures of the human pre-catalytic spliceosome and its precursor spliceosome. Cell Res., 28, 2018
6SWA	Mus musculus brain neocortex ribosome 60S bound to Ebp1 分子名称: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Kraushar, M.L, Sprink, T. 登録日 2019-09-20 公開日 2020-09-30 最終更新日 2021-02-17 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit. Mol.Cell, 81, 2021
8Q7N	cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, MINX pre-mRNA, Microfibrillar-associated protein 1, ... 著者 Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Urlaub, H, Stark, H, Luehrmann, R. 登録日 2023-08-16 公開日 2024-01-24 最終更新日 2024-08-07 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Cryo-EM analyses of dimerized spliceosomes provide new insights into the functions of B complex proteins. Embo J., 43, 2024
6J4I	A conserved and buried edge-to-face aromatic interaction in SUMO is vital for the SUMO pathway 分子名称: Small ubiquitin-related modifier 1 著者 Chatterjee, K.S, Das, R. 登録日 2019-01-09 公開日 2019-03-13 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 A conserved and buried edge-to-face aromatic interaction in small ubiquitin-like modifier (SUMO) has a role in SUMO stability and function. J.Biol.Chem., 294, 2019
8FLA	Human nuclear pre-60S ribosomal subunit (State K1) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (2.63 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8QPB	Cryo-EM Structure of Pre-B+ATP Complex (core part) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ... 著者 Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. 登録日 2023-10-01 公開日 2024-05-22 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
8QZS	Cryo-EM structure of the cross-exon B-like complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Microfibrillar-associated protein 1, NHP2-like protein 1, ... 著者 Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. 登録日 2023-10-29 公開日 2024-05-22 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
8QO9	Cryo-EM structure of a human spliceosomal B complex protomer 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, MINX pre-mRNA, Microfibrillar-associated protein 1, ... 著者 Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Urlaub, H, Stark, H, Luehrmann, R. 登録日 2023-09-28 公開日 2024-01-24 最終更新日 2024-08-07 実験手法 ELECTRON MICROSCOPY (5.29 Å) 主引用文献 Cryo-EM analyses of dimerized spliceosomes provide new insights into the functions of B complex proteins. Embo J., 43, 2024
8FLD	Human nuclear pre-60S ribosomal subunit (State L1) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.58 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8QPK	Cryo-EM Structure of Pre-B+5'ss Complex (core part) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ... 著者 Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. 登録日 2023-10-02 公開日 2024-05-22 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
8QPA	Cryo-EM Structure of Pre-B+5'ssLNG Complex (core part) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ... 著者 Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. 登録日 2023-10-01 公開日 2024-05-22 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
8R0B	Cryo-EM structure of the cross-exon pre-B+ATP complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ... 著者 Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. 登録日 2023-10-31 公開日 2024-05-22 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
8QOZ	Cryo-EM Structure of Pre-B+5'ss+ATPgammaS Complex (core part) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss RNA oligo, INOSITOL HEXAKISPHOSPHATE, ... 著者 Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. 登録日 2023-09-29 公開日 2024-05-22 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
8R0A	Cryo-EM structure of the cross-exon pre-B+5'ss complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ... 著者 Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. 登録日 2023-10-31 公開日 2024-05-22 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
8FKY	Human nucleolar pre-60S ribosomal subunit (State F) 分子名称: 28S rRNA, 5.8S rRNA, 60S ribosomal protein L10a, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (2.67 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
6JXU	SUMO1 bound to SLS4-SIM peptide from ICP0 分子名称: Small ubiquitin-related modifier, viral protein 著者 Hembram, D.S.S, Negi, H, Shet, D, Das, R. 登録日 2019-04-25 公開日 2020-02-05 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The Viral SUMO-Targeted Ubiquitin Ligase ICP0 is Phosphorylated and Activated by Host Kinase Chk2. J.Mol.Biol., 432, 2020

<234567891011121314151617>