8Q7N

cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region)

Summary for 8Q7N

• Entry DOI: 10.2210/pdb8q7n/pdb
• EMDB information: 18225
• Descriptor: U5 snRNA, WW domain-binding protein 4, MINX pre-mRNA, ... (21 entities in total)
• Functional Keywords: spliceosome, pre-catalytic spliceosome, spliceosomal b complex, splicing
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 21
• Total formula weight: 1427478.54

Authors

Zhang, Z.,Kumar, V.,Dybkov, O.,Will, C.L.,Urlaub, H.,Stark, H.,Luehrmann, R. (deposition date: 2023-08-16, release date: 2024-01-24)

• Primary citation: Zhang, Z.,Kumar, V.,Dybkov, O.,Will, C.L.,Urlaub, H.,Stark, H.,Luehrmann, R.; New insights into the functions of B complex proteins revealed by cryo-EM of dimerized spliceosomes; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.1 Å)