Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7S59
DownloadVisualize
BU of 7s59 by Molmil
Crystal structure of the tick evasin EVA-P974 complexed to a chimera made of human chemokines CCL7 and CCL8
分子名称: Evasin P974, SULFATE ION, chimera protein of C-C motif chemokine 7 and C-C motif chemokine 8,C-C motif chemokine 7
著者Bhusal, R.P, Devkota, S.R, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2021-09-10
公開日2022-03-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structure-guided engineering of tick evasins for targeting chemokines in inflammatory diseases.
Proc.Natl.Acad.Sci.USA, 119, 2022
7S58
DownloadVisualize
BU of 7s58 by Molmil
Crystal Structure of the tick evasin EVA-P974 complexed to human chemokine CCL7
分子名称: C-C motif chemokine 7, Evasin P974
著者Bhusal, R.P, Devkota, S.R, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2021-09-10
公開日2022-03-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Structure-guided engineering of tick evasins for targeting chemokines in inflammatory diseases.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VL9
DownloadVisualize
BU of 7vl9 by Molmil
Cryo-EM structure of the CCL15(26-92) bound CCR1-Gi complex
分子名称: C-C chemokine receptor type 1, CCL15(26-92), CHOLESTEROL, ...
著者Shao, Z, Shen, Q, Mao, C, Yao, B, Chen, L, Zhang, H, Shen, D, Zhang, C, Li, W, Du, X, Li, F, Ma, H, Chen, Z, Xu, H.E, Ying, S, Zhang, Y, Shen, H.
登録日2021-10-02
公開日2022-03-23
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Identification and mechanism of G protein-biased ligands for chemokine receptor CCR1.
Nat.Chem.Biol., 18, 2022
7VLA
DownloadVisualize
BU of 7vla by Molmil
Cryo-EM structure of the CCL15(27-92) bound CCR1-Gi complex
分子名称: C-C chemokine receptor type 1, CCL15(27-92), CHOLESTEROL, ...
著者Shao, Z, Shen, Q, Mao, C, Yao, B, Chen, L, Zhang, H, Shen, D, Zhang, C, Li, W, Du, X, Li, F, Ma, H, Chen, Z, Xu, H.E, Ying, S, Zhang, Y, Shen, H.
登録日2021-10-02
公開日2022-03-23
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Identification and mechanism of G protein-biased ligands for chemokine receptor CCR1.
Nat.Chem.Biol., 18, 2022
7XBX
DownloadVisualize
BU of 7xbx by Molmil
Cryo-EM structure of the human chemokine receptor CX3CR1 in complex with CX3CL1 and Gi1
分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Lu, M, Zhao, W, Han, S, Zhu, Y, Wu, B, Zhao, Q.
登録日2022-03-22
公開日2022-07-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Activation of the human chemokine receptor CX3CR1 regulated by cholesterol.
Sci Adv, 8, 2022
7SK8
DownloadVisualize
BU of 7sk8 by Molmil
Cryo-EM structure of human ACKR3 in complex with CXCL12, a small molecule partial agonist CCX662, an extracellular Fab, and an intracellular Fab
分子名称: (1R)-4-[7-(3-carboxypropoxy)-6-methylquinolin-8-yl]-1-{[2-(4-hydroxypiperidin-1-yl)-1,3-thiazol-4-yl]methyl}-1,4-diazepan-1-ium, Atypical chemokine receptor 3, CHOLESTEROL, ...
著者Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G.
登録日2021-10-19
公開日2022-07-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.
Sci Adv, 8, 2022
7SK5
DownloadVisualize
BU of 7sk5 by Molmil
Cryo-EM structure of ACKR3 in complex with CXCL12 and an intracellular Fab
分子名称: Anti-Fab nanobody, Atypical chemokine receptor 3, CHOLESTEROL, ...
著者Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G.
登録日2021-10-19
公開日2022-07-27
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.
Sci Adv, 8, 2022
7SK7
DownloadVisualize
BU of 7sk7 by Molmil
Cryo-EM structure of human ACKR3 in complex with CXCL12, a small molecule partial agonist CCX662, and an extracellular Fab
分子名称: (1R)-4-[7-(3-carboxypropoxy)-6-methylquinolin-8-yl]-1-{[2-(4-hydroxypiperidin-1-yl)-1,3-thiazol-4-yl]methyl}-1,4-diazepan-1-ium, Anti-Fab nanobody, Atypical chemokine receptor 3, ...
著者Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G.
登録日2021-10-19
公開日2022-07-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.
Sci Adv, 8, 2022
7SK3
DownloadVisualize
BU of 7sk3 by Molmil
Cryo-EM structure of ACKR3 in complex with CXCL12, an intracellular Fab, and an extracellular Fab
分子名称: Atypical chemokine receptor 3, CHOLESTEROL, CID24 Fab heavy chain, ...
著者Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G.
登録日2021-10-19
公開日2022-07-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.
Sci Adv, 8, 2022
7SK6
DownloadVisualize
BU of 7sk6 by Molmil
Cryo-EM structure of human ACKR3 in complex with chemokine N-terminal mutant CXCL12_LRHQ and an intracellular Fab
分子名称: Atypical chemokine receptor 3, CID24 Fab heavy chain, CID24 Fab light chain, ...
著者Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G.
登録日2021-10-19
公開日2022-07-27
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.
Sci Adv, 8, 2022
7SK4
DownloadVisualize
BU of 7sk4 by Molmil
Cryo-EM structure of ACKR3 in complex with chemokine N-terminal mutant CXCL12_LRHQ, an intracellular Fab, and an extracellular Fab
分子名称: Atypical chemokine receptor 3, CHOLESTEROL, CID24 Fab heavy chain, ...
著者Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G.
登録日2021-10-19
公開日2022-07-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.
Sci Adv, 8, 2022
7XA3
DownloadVisualize
BU of 7xa3 by Molmil
Cryo-EM structure of the CCL2 bound CCR2-Gi complex
分子名称: C-C motif chemokine 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Shao, Z, Tan, Y, Shen, Q, Yao, B, Hou, L, Qin, J, Xu, P, Mao, C, Chen, L, Zhang, H, Shen, D, Zhang, C, Li, W, Du, X, Li, F, Chen, Z, Jiang, Y, Xu, H.E, Ying, S, Ma, H, Zhang, Y, Shen, H.
登録日2022-03-17
公開日2022-08-24
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Molecular insights into ligand recognition and activation of chemokine receptors CCR2 and CCR3.
Cell Discov, 8, 2022
7T1E
DownloadVisualize
BU of 7t1e by Molmil
Structure of monomeric and dimeric human CCL20
分子名称: C-C motif chemokine 20, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Peterson, F.C, Riutta, S.J, Volkman, B.F.
登録日2021-12-01
公開日2022-12-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.459 Å)
主引用文献CCL20 and CCR6 in the pathogenesis and treatment of psoriasis and psoriatic arthritis
To Be Published
7SCS
DownloadVisualize
BU of 7scs by Molmil
Crystal Structure of the Tick Evasin EVA-AAM1001 Complexed to Human Chemokine CCL11
分子名称: Eotaxin, Evasin P1243
著者Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2021-09-29
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins.
Nat Commun, 14, 2023
7SCV
DownloadVisualize
BU of 7scv by Molmil
Crystal Structure of the Tick Evasin EVA-AAM1001 Complexed to Human Chemokine CCL17
分子名称: C-C motif chemokine 17, Evasin P1243
著者Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2021-09-29
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins.
Nat Commun, 14, 2023
7SCT
DownloadVisualize
BU of 7sct by Molmil
Crystal Structure of the Tick Evasin EVA-AAM1001 Complexed to Human Chemokine CCL16
分子名称: C-C motif chemokine 16, Evasin P1243
著者Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2021-09-29
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins.
Nat Commun, 14, 2023
8FJ3
DownloadVisualize
BU of 8fj3 by Molmil
Crystal Structure of the Tick Evasin EVA-AAM1001 Complexed to Human Chemokine CCL7(Y13A)
分子名称: C-C motif chemokine 7, Evasin P1243
著者Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2022-12-19
公開日2023-03-29
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins.
Nat Commun, 14, 2023
8FJ2
DownloadVisualize
BU of 8fj2 by Molmil
Crystal Structure of the Tick Evasin EVA-AAM1001(C8) Complexed to Human Chemokine CCL17
分子名称: C-C motif chemokine 17, Evasin P1243
著者Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2022-12-19
公開日2023-03-29
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins.
Nat Commun, 14, 2023
8FK8
DownloadVisualize
BU of 8fk8 by Molmil
Crystal Structure of the Tick Evasin EVA-AAM1001(L39P) Complexed to Human Chemokine CCL7
分子名称: C-C motif chemokine 7, Evasin P1243
著者Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2022-12-20
公開日2023-03-29
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins.
Nat Commun, 14, 2023
8FJ0
DownloadVisualize
BU of 8fj0 by Molmil
Crystal Structure of the Tick Evasin EVA-AAM1001(Y44A) Complexed to Human Chemokine CCL2
分子名称: C-C motif chemokine 2, Evasin P1243
著者Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2022-12-18
公開日2023-03-29
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins.
Nat Commun, 14, 2023
8FK6
DownloadVisualize
BU of 8fk6 by Molmil
Crystal Structure of the Tick Evasin EVA-AAM1001(Y44A) Complexed to Human Chemokine CCL7
分子名称: C-C motif chemokine 7, Evasin P1243
著者Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2022-12-20
公開日2023-03-29
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins.
Nat Commun, 14, 2023
7SCU
DownloadVisualize
BU of 7scu by Molmil
Crystal Structure of the Tick Evasin EVA-AAM1001 Complexed to Human Chemokine CCL7
分子名称: C-C motif chemokine 7, Evasin P1243
著者Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2021-09-29
公開日2023-04-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystal Structure of Tick Evasin EVA-AAM1001 complexed to human chemokine CCL7
To Be Published
8SKK
DownloadVisualize
BU of 8skk by Molmil
Crystal Structure of the Tick Evasin EVA-AAM1001(L39P) Complexed to Human Chemokine CCL17
分子名称: C-C motif chemokine 17, Evasin P1243
著者Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2023-04-19
公開日2023-05-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of the Tick Evasin EVA-AAM1001(L39P) Complexed to Human Chemokine CCL7
To be Published
8IC0
DownloadVisualize
BU of 8ic0 by Molmil
Cryo-EM structure of CXCL8 bound C-X-C chemokine receptor 1 in complex with Gi heterotrimer
分子名称: C-X-C chemokine receptor type 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Ishimoto, N, Park, J.H, Park, S.Y.
登録日2023-02-10
公開日2023-07-19
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Structural basis of CXC chemokine receptor 1 ligand binding and activation.
Nat Commun, 14, 2023
8HNK
DownloadVisualize
BU of 8hnk by Molmil
CXCR3-DNGi complex activated by CXCL11
分子名称: C-X-C motif chemokine 11, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Jiao, H.Z, Hu, H.L.
登録日2022-12-08
公開日2023-11-29
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Structural insights into the activation and inhibition of CXC chemokine receptor 3.
Nat.Struct.Mol.Biol., 31, 2024

221051

件を2024-06-12に公開中

PDB statisticsPDBj update infoContact PDBjnumon