7SCV
Crystal Structure of the Tick Evasin EVA-AAM1001 Complexed to Human Chemokine CCL17
Summary for 7SCV
Entry DOI | 10.2210/pdb7scv/pdb |
Descriptor | Evasin P1243, C-C motif chemokine 17 (3 entities in total) |
Functional Keywords | inflammation, chemokine, ticks, evasin, immune system |
Biological source | Amblyomma americanum (Lone star tick) More |
Total number of polymer chains | 2 |
Total formula weight | 19210.75 |
Authors | Devkota, S.R.,Bhusal, R.P.,Aryal, P.,Wilce, M.C.J.,Stone, M.J. (deposition date: 2021-09-29, release date: 2023-03-29, Last modification date: 2023-10-25) |
Primary citation | Devkota, S.R.,Aryal, P.,Pokhrel, R.,Jiao, W.,Perry, A.,Panjikar, S.,Payne, R.J.,Wilce, M.C.J.,Bhusal, R.P.,Stone, M.J. Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins. Nat Commun, 14:4204-4204, 2023 Cited by PubMed: 37452046DOI: 10.1038/s41467-023-39879-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.01 Å) |
Structure validation
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