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PDB: 11 results

7XBD
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BU of 7xbd by Molmil
Cryo-EM structure of human galanin receptor 2
Descriptor: Galanin, Galanin receptor type 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Ishimoto, N, Kita, S, Park, S.Y.
Deposit date:2022-03-21
Release date:2022-07-13
Last modified:2022-08-10
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Structure of the human galanin receptor 2 bound to galanin and Gq reveals the basis of ligand specificity and how binding affects the G-protein interface.
Plos Biol., 20, 2022
8IC0
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BU of 8ic0 by Molmil
Cryo-EM structure of CXCL8 bound C-X-C chemokine receptor 1 in complex with Gi heterotrimer
Descriptor: C-X-C chemokine receptor type 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Ishimoto, N, Park, J.H, Park, S.Y.
Deposit date:2023-02-10
Release date:2023-07-19
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Structural basis of CXC chemokine receptor 1 ligand binding and activation.
Nat Commun, 14, 2023
8H2G
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Cryo-EM structure of niacin bound human hydroxy-carboxylic acid receptor 2 in complex with Gi heterotrimer
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Park, J.H, Ishimoto, N, Park, S.Y.
Deposit date:2022-10-06
Release date:2023-10-11
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Structural basis for hydroxy-carboxylic acid receptor 2 activation and allosteric mechanism
To Be Published
7FCI
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BU of 7fci by Molmil
human NTCP in complex with YN69083 Fab
Descriptor: Fab Heavy chain, Fab Light chain, Sodium/bile acid cotransporter
Authors:Park, J.H, Iwamoto, M, Yun, J.H, Uchikubo-Kamo, T, Son, D, Jin, Z, Yoshida, H, Ohki, M, Ishimoto, N, Mizutani, K, Oshima, M, Muramatsu, M, Wakita, T, Shirouzu, M, Liu, K, Uemura, T, Nomura, N, Iwata, S, Watashi, K, Tame, J.R.H, Nishizawa, T, Lee, W, Park, S.Y.
Deposit date:2021-07-14
Release date:2022-05-25
Last modified:2022-07-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into the HBV receptor and bile acid transporter NTCP.
Nature, 606, 2022
7WJ5
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Cryo-EM structure of human somatostatin receptor 2 complex with its agonist somatostatin delineates the ligand binding specificity
Descriptor: Gai1 antibody (scfv16), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Heo, Y.S, Yoon, E.J, Jeon, Y.E, Yun, J.-H, Ishimoto, N, Woo, H, Park, S.Y, Song, J, Lee, W.T.
Deposit date:2022-01-05
Release date:2022-07-13
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Cryo-EM structure of the human somatostatin receptor 2 complex with its agonist somatostatin delineates the ligand-binding specificity.
Elife, 11, 2022
8I7W
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BU of 8i7w by Molmil
Cryo-EM structure of GSK256073 bound human hydroxy-carboxylic acid receptor 2 in complex with Gi heterotrimer
Descriptor: 8-chloranyl-3-pentyl-7H-purine-2,6-dione, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Park, J.H, Ishimoto, N, Park, S.Y.
Deposit date:2023-02-02
Release date:2024-02-07
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2.
Nat Commun, 14, 2023
8I7V
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BU of 8i7v by Molmil
Cryo-EM structure of Acipimox bound human hydroxy-carboxylic acid receptor 2 in complex with Gi heterotrimer
Descriptor: 5-methyl-4-oxidanyl-pyrazin-4-ium-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Park, J.H, Ishimoto, N, Park, S.Y.
Deposit date:2023-02-02
Release date:2024-02-07
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2.
Nat Commun, 14, 2023
8K5D
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BU of 8k5d by Molmil
Cryo-EM structure of GSK256073 bound human hydroxy-carboxylic acid receptor 2 (Local refinement)
Descriptor: 8-chloranyl-3-pentyl-7H-purine-2,6-dione, Human hydroxycarboxylic acid receptor 2
Authors:Park, J.H, Ishimoto, N, Park, S.Y.
Deposit date:2023-07-21
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2
Nat Commun, 14, 2023
8K5B
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Cryo-EM structure of niacin bound human hydroxy-carboxylic acid receptor 2 (Local refinement)
Descriptor: Human Hydroxycarboxylic acid receptor 2, NICOTINIC ACID
Authors:Park, J.H, Ishimoto, N, Park, S.Y.
Deposit date:2023-07-21
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2
Nat Commun, 14, 2023
8K5C
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BU of 8k5c by Molmil
Cryo-EM structure of Acipimox bound human hydroxy-carboxylic acid receptor 2 (Local refinement)
Descriptor: 5-methyl-4-oxidanyl-pyrazin-4-ium-2-carboxylic acid, Human hydroxycarboxylic acid receptor 2
Authors:Park, J.H, Ishimoto, N, Park, S.Y.
Deposit date:2023-07-21
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2
Nat Commun, 14, 2023
7VDN
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High resolution crystal structure of Sperm Whale Myoglobin in the carbonmonoxy form
Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Shibayama, N, Sato-Tomita, A, Ishimoto, N, Park, S.Y.
Deposit date:2021-09-07
Release date:2022-09-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (0.93 Å)
Cite:X-ray fluorescence holography of biological metal sites: Application to myoglobin.
Biochem.Biophys.Res.Commun., 635, 2022

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