7FCI

human NTCP in complex with YN69083 Fab

Summary for 7FCI

Entry DOI	10.2210/pdb7fci/pdb
EMDB information	31526
Descriptor	Sodium/bile acid cotransporter, Fab Light chain, Fab Heavy chain (3 entities in total)
Functional Keywords	transporter, transport protein, transport protein-immune system complex, transport protein/immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	89330.38
Authors	Park, J.H.,Iwamoto, M.,Yun, J.H.,Uchikubo-Kamo, T.,Son, D.,Jin, Z.,Yoshida, H.,Ohki, M.,Ishimoto, N.,Mizutani, K.,Oshima, M.,Muramatsu, M.,Wakita, T.,Shirouzu, M.,Liu, K.,Uemura, T.,Nomura, N.,Iwata, S.,Watashi, K.,Tame, J.R.H.,Nishizawa, T.,Lee, W.,Park, S.Y. (deposition date: 2021-07-14, release date: 2022-05-25, Last modification date: 2022-07-13)
Primary citation	Park, J.H.,Iwamoto, M.,Yun, J.H.,Uchikubo-Kamo, T.,Son, D.,Jin, Z.,Yoshida, H.,Ohki, M.,Ishimoto, N.,Mizutani, K.,Oshima, M.,Muramatsu, M.,Wakita, T.,Shirouzu, M.,Liu, K.,Uemura, T.,Nomura, N.,Iwata, S.,Watashi, K.,Tame, J.R.H.,Nishizawa, T.,Lee, W.,Park, S.Y. Structural insights into the HBV receptor and bile acid transporter NTCP. Nature, 606:1027-1031, 2022 Cited by PubMed: 35580630 DOI: 10.1038/s41586-022-04857-0 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation