8K5D

Cryo-EM structure of GSK256073 bound human hydroxy-carboxylic acid receptor 2 (Local refinement)

Summary for 8K5D

• Entry DOI: 10.2210/pdb8k5d/pdb
• EMDB information: 36902
• Descriptor: Human hydroxycarboxylic acid receptor 2, 8-chloranyl-3-pentyl-7H-purine-2,6-dione (2 entities in total)
• Functional Keywords: gpcr, g-protein, membrane protein, signaling
• Biological source: Homo sapiens; More
• Total number of polymer chains: 1
• Total formula weight: 54576.99

Authors

Park, J.H.,Ishimoto, N.,Park, S.Y. (deposition date: 2023-07-21, release date: 2023-11-22)

• Primary citation: Park, J.H.,Kawakami, K.,Ishimoto, N.,Ikuta, T.,Ohki, M.,Ekimoto, T.,Ikeguchi, M.,Lee, D.S.,Lee, Y.H.,Tame, J.R.H.,Inoue, A.,Park, S.Y.; Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2; Nat Commun, 14:7150-, 2023; DOI: 10.1038/s41467-023-42764-8

Experimental method

ELECTRON MICROSCOPY (3.74 Å)