8K5C
Cryo-EM structure of Acipimox bound human hydroxy-carboxylic acid receptor 2 (Local refinement)
Summary for 8K5C
| Entry DOI | 10.2210/pdb8k5c/pdb |
| EMDB information | 36901 |
| Descriptor | Human hydroxycarboxylic acid receptor 2, 5-methyl-4-oxidanyl-pyrazin-4-ium-2-carboxylic acid (2 entities in total) |
| Functional Keywords | gpcr, g-protein, membrane protein, acipimox, signaling |
| Biological source | Homo sapiens More |
| Total number of polymer chains | 1 |
| Total formula weight | 54475.43 |
| Authors | Park, J.H.,Ishimoto, N.,Park, S.Y. (deposition date: 2023-07-21, release date: 2023-11-22, Last modification date: 2024-05-08) |
| Primary citation | Park, J.H.,Kawakami, K.,Ishimoto, N.,Ikuta, T.,Ohki, M.,Ekimoto, T.,Ikeguchi, M.,Lee, D.S.,Lee, Y.H.,Tame, J.R.H.,Inoue, A.,Park, S.Y. Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2. Nat Commun, 14:7150-7150, 2023 Cited by PubMed: 37932263DOI: 10.1038/s41467-023-42764-8 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.13 Å) |
Structure validation
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