7WJ5
Cryo-EM structure of human somatostatin receptor 2 complex with its agonist somatostatin delineates the ligand binding specificity
Summary for 7WJ5
Entry DOI | 10.2210/pdb7wj5/pdb |
EMDB information | 32543 |
Related PRD ID | PRD_001216 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total) |
Functional Keywords | gpcr, agonist, heterotrimeric g-protein, camp, membrane protein, membrane protein-immune system complex, membrane protein/immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 176136.43 |
Authors | Heo, Y.S.,Yoon, E.J.,Jeon, Y.E.,Yun, J.-H.,Ishimoto, N.,Woo, H.,Park, S.Y.,Song, J.,Lee, W.T. (deposition date: 2022-01-05, release date: 2022-07-13) |
Primary citation | Heo, Y.,Yoon, E.,Jeon, Y.E.,Yun, J.H.,Ishimoto, N.,Woo, H.,Park, S.Y.,Song, J.J.,Lee, W. Cryo-EM structure of the human somatostatin receptor 2 complex with its agonist somatostatin delineates the ligand-binding specificity. Elife, 11:-, 2022 Cited by PubMed: 35446253DOI: 10.7554/eLife.76823 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.72 Å) |
Structure validation
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