8H2G
Cryo-EM structure of niacin bound human hydroxy-carboxylic acid receptor 2 in complex with Gi heterotrimer
Summary for 8H2G
Entry DOI | 10.2210/pdb8h2g/pdb |
EMDB information | 34437 |
Descriptor | Hydroxy-carboxylic acid receptor 2, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total) |
Functional Keywords | gpcr, hydroxycarboxylic acid, g-protein, membrane protein, niacin, signaling |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 168502.94 |
Authors | |
Primary citation | Park, J.H.,Ishimoto, N.,Kawakami, K.,Ikuta, T.,Ohki, M.,Ekimoto, T.,Ikeguchi, M.,Lee, D.S.,Lee, Y.H.,Tame, J.R.H.,Inoue, A.,Park, S.Y. Structural basis for hydroxy-carboxylic acid receptor 2 activation and allosteric mechanism To Be Published, |
Experimental method | ELECTRON MICROSCOPY (3.01 Å) |
Structure validation
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