7XBX
Cryo-EM structure of the human chemokine receptor CX3CR1 in complex with CX3CL1 and Gi1
Summary for 7XBX
Entry DOI | 10.2210/pdb7xbx/pdb |
EMDB information | 33108 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (5 entities in total) |
Functional Keywords | g protein-coupled receptor, chemokine receptor, cx3cr1, cx3cl1, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 138885.65 |
Authors | |
Primary citation | Lu, M.,Zhao, W.,Han, S.,Lin, X.,Xu, T.,Tan, Q.,Wang, M.,Yi, C.,Chu, X.,Yang, W.,Zhu, Y.,Wu, B.,Zhao, Q. Activation of the human chemokine receptor CX3CR1 regulated by cholesterol. Sci Adv, 8:eabn8048-eabn8048, 2022 Cited by PubMed: 35767622DOI: 10.1126/sciadv.abn8048 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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