7VLA
Cryo-EM structure of the CCL15(27-92) bound CCR1-Gi complex
Summary for 7VLA
Entry DOI | 10.2210/pdb7vla/pdb |
EMDB information | 32022 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total) |
Functional Keywords | gpcr, ccr1, chemokine receptor, membrne protein, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 164152.53 |
Authors | |
Primary citation | Shao, Z.,Shen, Q.,Yao, B.,Mao, C.,Chen, L.N.,Zhang, H.,Shen, D.D.,Zhang, C.,Li, W.,Du, X.,Li, F.,Ma, H.,Chen, Z.H.,Xu, H.E.,Ying, S.,Zhang, Y.,Shen, H. Identification and mechanism of G protein-biased ligands for chemokine receptor CCR1. Nat.Chem.Biol., 18:264-271, 2022 Cited by PubMed: 34949837DOI: 10.1038/s41589-021-00918-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.7 Å) |
Structure validation
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