7S59
Crystal structure of the tick evasin EVA-P974 complexed to a chimera made of human chemokines CCL7 and CCL8
Summary for 7S59
Entry DOI | 10.2210/pdb7s59/pdb |
Descriptor | Evasin P974, chimera protein of C-C motif chemokine 7 and C-C motif chemokine 8,C-C motif chemokine 7, SULFATE ION, ... (4 entities in total) |
Functional Keywords | inflammation, evasin, chemokine binder, evasin-chemokine complex, immune system |
Biological source | Amblyomma cajennense (Cayenne tick, Acarus cajennensis) More |
Total number of polymer chains | 4 |
Total formula weight | 37409.14 |
Authors | Bhusal, R.P.,Devkota, S.R.,Aryal, P.,Wilce, M.C.J.,Stone, M.J. (deposition date: 2021-09-10, release date: 2022-03-16, Last modification date: 2023-10-18) |
Primary citation | Bhusal, R.P.,Aryal, P.,Devkota, S.R.,Pokhrel, R.,Gunzburg, M.J.,Foster, S.R.,Lim, H.D.,Payne, R.J.,Wilce, M.C.J.,Stone, M.J. Structure-guided engineering of tick evasins for targeting chemokines in inflammatory diseases. Proc.Natl.Acad.Sci.USA, 119:-, 2022 Cited by PubMed: 35217625DOI: 10.1073/pnas.2122105119 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.39 Å) |
Structure validation
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