7S59

Crystal structure of the tick evasin EVA-P974 complexed to a chimera made of human chemokines CCL7 and CCL8

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (1, 3)	Evasin P974	polymer	85	9702.1	2	UniProt (A0A023FDY8) Pfam (PF19429)	Amblyomma cajennense (Cayenne tick Acarus cajennensis)
2	C, D (4, 2)	chimera protein of C-C motif chemokine 7 and C-C motif chemokine 8,C-C motif chemokine 7	polymer	76	8906.4	2	UniProt (P80075) UniProt (P80098) Pfam (PF00048)	Homo sapiens (Human)	HC14,Monocyte chemoattractant protein 2,Monocyte chemotactic protein 2,MCP-2,Small-inducible cytokine A8,Monocyte chemoattractant protein 3,Monocyte chemotactic protein 3,MCP-3,NC28,Small-inducible cytokine A7
3	E, F (1, 4)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4	G, H (1, 4)	water	water		18.0	9	Chemie (HOH)

Sequence modifications

4, 2: 1 - 15 (UniProt: P80075)
4, 2: 16 - 76 (UniProt: P80098)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	37217.0
Non-Polymers*	Number of molecules	2
	Total formula weight	192.1
All*	Total formula weight	37409.1

*Water molecules are not included.