PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

---

4QZ4	yCP beta5-A49S mutant in complex with the epoxyketone inhibitor ONX 0914 分子名称: 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... 著者 Huber, E.M, Heinemeyer, W, Groll, M. 登録日 2014-07-27 公開日 2015-02-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
4QVQ	yCP beta5-M45I mutant in complex with bortezomib 分子名称: CHLORIDE ION, MAGNESIUM ION, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, ... 著者 Huber, E.M, Heinemeyer, W, Groll, M. 登録日 2014-07-15 公開日 2015-02-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
4QWI	yCP beta5-A49S-mutant in complex with carfilzomib 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ... 著者 Huber, E.M, Heinemeyer, W, Groll, M. 登録日 2014-07-16 公開日 2015-02-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
4ISW	Crystal Structure of Phosphorylated C.elegans Thymidylate Synthase in Complex with dUMP 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Thymidylate synthase 著者 Wilk, P, Dowiercial, A, Banaszak, K, Jarmula, A, Rypniewski, W, Rode, W. 登録日 2013-01-17 公開日 2013-12-11 最終更新日 2014-01-15 実験手法 X-RAY DIFFRACTION (3.14 Å) 主引用文献 Crystal structure of phosphoramide-phosphorylated thymidylate synthase reveals pSer127, reflecting probably pHis to pSer phosphotransfer. Bioorg.Chem., 52C, 2013
2A21	Aquifex aeolicus KDO8PS in complex with PEP, PO4, and Zn2+ 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, PHOSPHATE ION, PHOSPHOENOLPYRUVATE, ... 著者 Kona, F, Xu, X, Lu, J, Martin, P, Gatti, D.L. 登録日 2005-06-21 公開日 2006-06-20 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Electronic structure of the metal center in the Cd(2+), Zn(2+), and Cu(2+) substituted forms of KDO8P synthase: implications for catalysis. Biochemistry, 48, 2009
2AF5	2.5A X-ray Structure of Engineered OspA protein 分子名称: Engineered Outer Surface Protein A (OspA) with the inserted two beta-hairpins 著者 Makabe, K, Mcelheny, D, Tereshko, V, Hilyard, A, Koide, A, Koide, S. 登録日 2005-07-25 公開日 2006-08-01 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Atomic structures of peptide self-assembly mimics. Proc.Natl.Acad.Sci.Usa, 103, 2006
4R02	yCP in complex with BSc4999 (alpha-Keto Phenylamide) 分子名称: MAGNESIUM ION, N-[(benzyloxy)carbonyl]-L-leucyl-N-{(2S,3S)-1-[(2,4-dimethylphenyl)amino]-2-hydroxy-5-methyl-1-oxohexan-3-yl}-L-leucinamide, Probable proteasome subunit alpha type-7, ... 著者 Voss, C, Scholz, C, Knorr, S, Beck, P, Stein, M, Zall, A, Kuckelkorn, U, Kloetzel, P.-M, Groll, M, Hamacher, K, Schmidt, B. 登録日 2014-07-29 公開日 2014-08-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 alpha-Keto Phenylamides as P1'-Extended Proteasome Inhibitors. Chemmedchem, 9, 2014
4IYD	Insulin glargine crystal structure 1 分子名称: Insulin A chain, Insulin B chain 著者 Barba de la Rosa, A.P, Lara-Gonzalez, S, Montero-Moran, G.M, Escobedo-Moratilla, A. 登録日 2013-01-28 公開日 2014-02-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Physicochemical and structural analysis of a biosimilar insulin glargine formulation and its reference to be published
4J3Z	Crystal structure of mandelate racemase/muconate lactonizing enzyme from Jannaschia sp. CCS1 分子名称: Mandelate racemase/muconate lactonizing enzyme 著者 Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Zenchek, W, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2013-02-06 公開日 2013-03-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of mandelate racemase/muconate lactonizing enzyme from Jannaschia sp. CCS1 To be Published
2A19	PKR kinase domain- eIF2alpha- AMP-PNP complex. 分子名称: Eukaryotic translation initiation factor 2 alpha subunit, Interferon-induced, double-stranded RNA-activated protein kinase, ... 著者 Dar, A.C, Dever, T.E, Sicheri, F. 登録日 2005-06-19 公開日 2005-09-27 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Higher-Order Substrate Recognition of eIF2alpha by the RNA-Dependent Protein Kinase PKR. Cell(Cambridge,Mass.), 122, 2005
3LT5	X-ray Crystallographic structure of a Pseudomonas Aeruginosa Azoreductase in complex with balsalazide 分子名称: (3E)-3-({4-[(2-carboxyethyl)carbamoyl]phenyl}hydrazono)-6-oxocyclohexa-1,4-diene-1-carboxylic acid, FLAVIN MONONUCLEOTIDE, FMN-dependent NADH-azoreductase 1, ... 著者 Ryan, A, Laurieri, N, Westwood, I, Wang, C.-J, Lowe, E, Sim, E. 登録日 2010-02-15 公開日 2010-05-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A Novel Mechanism for Azoreduction J.Mol.Biol., 400, 2010
1ZYR	Structure of Thermus thermophilus RNA polymerase holoenzyme in complex with the antibiotic streptolydigin 分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase omega chain, ... 著者 Tuske, S, Sarafianos, S.G, Wang, X, Hudson, B, Sineva, E, Mukhopadhyay, J, Birktoft, J.J, Leroy, O, Ismail, S, Clark, A.D, Dharia, C, Napoli, A, Laptenko, O, Lee, J, Borukhov, S, Ebright, R.H, Arnold, E. 登録日 2005-06-10 公開日 2005-09-13 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation. Cell(Cambridge,Mass.), 122, 2005
1ZO8	X-ray Structure of the haloalcohol dehalogenase HheC of Agrobacterium radiobacter AD1 in complex with (S)-para-nitrostyrene oxide, with a water molecule in the halide-binding site 分子名称: (S)-PARA-NITROSTYRENE OXIDE, halohydrin dehalogenase 著者 de Jong, R.M, Tiesinga, J.J.W, Tang, L, Villa, A, Janssen, D.B, Dijkstra, B.W. 登録日 2005-05-12 公開日 2005-10-04 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Basis for the Enantioselectivity of an Epoxide Ring Opening Reaction Catalyzed by Halo Alcohol Dehalogenase HheC. J.Am.Chem.Soc., 127, 2005
4RUR	Yeast 20S proteasome in complex with the alkaloid indolo-phakellin (4) 分子名称: (2E,3aR,14aS)-9-bromo-2-imino-1,2,3,5,6,14a-hexahydro-4H,8H-imidazo[4',5':5,6]pyrrolo[1',2':4,5]pyrazino[1,2-a]indol-8-one, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... 著者 Beck, P, Lansdell, T.A, Hewlett, N.M, Tepe, J.J, Groll, M. 登録日 2014-11-21 公開日 2014-12-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Indolo-Phakellins as beta 5-Specific Noncovalent Proteasome Inhibitors. Angew.Chem.Int.Ed.Engl., 54, 2015
1Z6O	Crystal Structure of Trichoplusia ni secreted ferritin 分子名称: CALCIUM ION, FE (III) ION, Ferritin heavy chain, ... 著者 Hamburger, A.E, West Jr, A.P, Hamburger, Z.A, Hamburger, P, Bjorkman, P.J. 登録日 2005-03-22 公開日 2005-05-24 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Crystal structure of a secreted insect ferritin reveals a symmetrical arrangement of heavy and light chains. J.Mol.Biol., 349, 2005
1ZF3	ATC Four-stranded DNA Holliday Junction 分子名称: 5'-D(*CP*CP*GP*AP*TP*AP*TP*CP*GP*G)-3', CALCIUM ION 著者 Hays, F.A, Teegarden, A.T, Jones, Z.J.R, Harms, M, Raup, D, Watson, J, Cavaliere, E, Ho, P.S. 登録日 2005-04-19 公開日 2005-05-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 How sequence defines structure: a crystallographic map of DNA structure and conformation. Proc.Natl.Acad.Sci.Usa, 102, 2005
1ZFH	TTA Duplex B-DNA 分子名称: 5'-D(*CP*CP*TP*AP*AP*TP*TP*AP*GP*G)-3' 著者 Hays, F.A, Teegarden, A.T, Jones, Z.J.R, Harms, M, Raup, D, Watson, J, Cavaliere, E, Ho, P.S. 登録日 2005-04-20 公開日 2005-05-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 How sequence defines structure: a crystallographic map of DNA structure and conformation. Proc.Natl.Acad.Sci.Usa, 102, 2005
3PSX	Crystal structure of the KT2 mutant of cytochrome P450 BM3 分子名称: Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE 著者 Yang, W, Whitehouse, C.J.C, Yorke, J.A, Bell, S.G, Zhou, W, Bartlam, M, Wong, L.L, Rao, Z. 登録日 2010-12-02 公開日 2011-12-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure, electronic properties and catalytic behaviour of an activity-enhancing CYP102A1 (P450(BM3)) variant Dalton Trans, 40, 2011
4J50	Crystal Structure of an Expanded RNA CAG Repeat 分子名称: PHOSPHATE ION, RNA (5'-R(*UP*UP*GP*GP*GP*CP*CP*AP*GP*CP*AP*GP*CP*AP*GP*GP*UP*CP*C)-3') 著者 Park, H, Disney, M.D. 登録日 2013-02-07 公開日 2013-02-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 A dynamic structural model of expanded RNA CAG repeats: a refined X-ray structure and computational investigations using molecular dynamics and umbrella sampling simulations. J.Am.Chem.Soc., 135, 2013
1ZDJ	STRUCTURE OF BACTERIOPHAGE COAT PROTEIN-LOOP RNA COMPLEX 分子名称: PROTEIN (MS2 PROTEIN CAPSID), RNA (5'-R(*GP*GP*AP*UP*CP*AP*CP*C)-3') 著者 Grahn, E, Stonehouse, N, Valegard, K, Vandenworm, S, Liljas, L. 登録日 1997-12-18 公開日 1998-07-08 最終更新日 2023-04-19 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystallographic studies of RNA hairpins in complexes with recombinant MS2 capsids: implications for binding requirements. RNA, 5, 1999
3PVM	Structure of Complement C5 in Complex with CVF 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, Complement C5 著者 Laursen, N.S, Andersen, K.R, Braren, I, Sottrup-Jensen, L, Spillner, E, Andersen, G.R. 登録日 2010-12-07 公開日 2011-01-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (4.3 Å) 主引用文献 Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex. Embo J., 30, 2011
1YXA	Serpina3n, a murine orthologue of human antichymotrypsin 分子名称: serine (or cysteine) proteinase inhibitor, clade A, member 3N 著者 Horvath, A.J, Irving, J.A, Law, R.H, Rossjohn, J, Bottomley, S.P, Quinsey, N.S, Pike, R.N, Coughlin, P.B, Whisstock, J.C. 登録日 2005-02-20 公開日 2005-09-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins. J.Biol.Chem., 280, 2005
3KRD	Crystal Structure of Mycobacterium Tuberculosis Proteasome in complex with Fellutamide B 分子名称: (3R)-3-HYDROXYDODECANOIC ACID, Fellutamide B, Proteasome subunit alpha, ... 著者 Li, D, Li, H. 登録日 2009-11-18 公開日 2010-09-29 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Fellutamide B is a potent inhibitor of the Mycobacterium tuberculosis proteasome. Arch.Biochem.Biophys., 501, 2010
4ROE	Human TFIIB-related factor 2 (Brf2) and TBP bound to RPPH1 promoter 分子名称: MAGNESIUM ION, Non-template strand, TATA-box-binding protein, ... 著者 Vannini, A, Gouge, J, Satia, K, Guthertz, N. 登録日 2014-10-28 公開日 2015-12-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2. Cell(Cambridge,Mass.), 163, 2015
2A47	Crystal structure of amFP486 H199T 分子名称: BETA-MERCAPTOETHANOL, GFP-like fluorescent chromoprotein amFP486 著者 Henderson, J.N, Remington, S.J. 登録日 2005-06-28 公開日 2005-08-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Crystal structures and mutational analysis of amFP486, a cyan fluorescent protein from Anemonia majano Proc.Natl.Acad.Sci.Usa, 102, 2005

<686687688689690691692693694695696697698699700701>