4IYD

Insulin glargine crystal structure 1

Summary for 4IYD

Related4IYF
DescriptorInsulin A chain, Insulin B chain (3 entities in total)
Functional Keywordshormone
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains2
Total molecular weight5659.5
Authors
Barba de la Rosa, A.P.,Lara-Gonzalez, S.,Montero-Moran, G.M.,Escobedo-Moratilla, A. (deposition date: 2013-01-28, release date: 2014-02-12)
Primary citation
Barba de la Rosa, A.P.,Lara-Gonzalez, S.,Montero-Moran, G.M.,Escobedo-Moratilla, A.,Perez-Urizar, J.T.
Physicochemical and structural analysis of a biosimilar insulin glargine formulation and its reference
to be published,
Experimental method
X-RAY DIFFRACTION (1.66 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2361000MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution