6XAT
| Crystal structure of the human FoxP4 DNA binding Domain | 分子名称: | FOXP4 protein, SODIUM ION | 著者 | VIllalobos, P, Castro-Fernandez, V, Medina, E, Gonzalez-Ordenes, F, Maturana, P, Herrera-Morande, A, Ramirez-Sarmiento, C.A, Babul, J. | 登録日 | 2020-06-04 | 公開日 | 2021-06-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Unraveling the folding and dimerization properties of the human FoxP subfamily of transcription factors. Febs Lett., 597, 2023
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7AUD
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7VPX
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8HAL
| Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 1 | 分子名称: | CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ... | 著者 | Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. | 登録日 | 2022-10-26 | 公開日 | 2023-05-17 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
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8HAM
| Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 2 | 分子名称: | CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ... | 著者 | Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. | 登録日 | 2022-10-26 | 公開日 | 2023-05-17 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
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8HAN
| Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 3 | 分子名称: | CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ... | 著者 | Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. | 登録日 | 2022-10-26 | 公開日 | 2023-05-17 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
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5D90
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4NB3
| Crystal structure of RPA70N in complex with a 3,4 dichlorophenylalanine ATRIP derived peptide | 分子名称: | 3,4 dichlorophenylalanine ATRIP derived peptide, Replication protein A 70 kDa DNA-binding subunit | 著者 | Feldkamp, M.D, Frank, A.O, Vangamudi, B, Souza-Fagundes, E.M, Luzwik, J.W, Cortez, D, Olejniczak, O.T, Waterson, A.G, Rossanese, O.W, Fesik, S.W, Chazin, W.J. | 登録日 | 2013-10-22 | 公開日 | 2014-02-26 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Discovery of a Potent Stapled Helix Peptide That Binds to the 70N Domain of Replication Protein A. J.Med.Chem., 57, 2014
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2AGO
| Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis | 分子名称: | CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*CP*G)-3'), DNA (5'-D(*TP*TP*TP*TP*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ... | 著者 | Ling, H, Yang, W. | 登録日 | 2005-07-27 | 公開日 | 2005-09-06 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis. Embo J., 24, 2005
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2GM4
| An activated, tetrameric gamma-delta resolvase: Hin chimaera bound to cleaved DNA | 分子名称: | 5'-D(*CP*AP*GP*TP*GP*TP*CP*CP*GP*AP*TP*AP*AP*TP*TP*TP*AP*TP*AP*AP*A)-3', 5'-D(*TP*TP*AP*TP*CP*GP*GP*AP*CP*AP*CP*TP*G)-3', Transposon gamma-delta resolvase | 著者 | Kamtekar, S, Ho, R.S, Li, W, Steitz, T.A. | 登録日 | 2006-04-05 | 公開日 | 2006-06-27 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Implications of structures of synaptic tetramers of gamma delta resolvase for the mechanism of recombination. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2AGP
| Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*(DOC)-3'), ... | 著者 | Ling, H, Yang, W. | 登録日 | 2005-07-27 | 公開日 | 2005-09-06 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis. Embo J., 24, 2005
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7CVQ
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7CVO
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6ZY7
| Cryo-EM structure of the entire Human topoisomerase II alpha in State 1 | 分子名称: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), ... | 著者 | Vanden Broeck, A, Lamour, V. | 登録日 | 2020-07-30 | 公開日 | 2021-05-26 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.64 Å) | 主引用文献 | Structural basis for allosteric regulation of Human Topoisomerase II alpha. Nat Commun, 12, 2021
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6ZY8
| Cryo-EM structure of the entire Human topoisomerase II alpha in State 2 | 分子名称: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), ... | 著者 | Vanden Broeck, A, Lamour, V. | 登録日 | 2020-07-30 | 公開日 | 2021-05-26 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (7.4 Å) | 主引用文献 | Structural basis for allosteric regulation of Human Topoisomerase II alpha. Nat Commun, 12, 2021
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7YI2
| Cryo-EM structure of Rpd3S in loose-state Rpd3S-NCP complex | 分子名称: | Chromatin modification-related protein EAF3, Histone deacetylase RPD3, Transcriptional regulatory protein RCO1, ... | 著者 | Li, H.T, Yan, C.Y, Guan, H.P, Wang, P. | 登録日 | 2022-07-14 | 公開日 | 2023-06-14 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S. Nature, 620, 2023
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7YI4
| Cryo-EM structure of Rpd3S complex bound to H3K36me3 nucleosome in close state | 分子名称: | Chromatin modification-related protein EAF3, Histone H2A, Histone H2B 1.1, ... | 著者 | Li, H.T, Yan, C.Y, Guan, H.P, Wang, P. | 登録日 | 2022-07-14 | 公開日 | 2023-06-14 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | 主引用文献 | Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S. Nature, 620, 2023
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7YI5
| Cryo-EM structure of Rpd3S complex bound to H3K36me3 nucleosome in loose state | 分子名称: | Chromatin modification-related protein EAF3, Histone H2A, Histone H2B 1.1, ... | 著者 | Li, H.T, Yan, C.Y, Guan, H.P, Wang, P. | 登録日 | 2022-07-14 | 公開日 | 2023-06-14 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | 主引用文献 | Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S. Nature, 620, 2023
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4XQN
| Crystal structure of AgrA LytTR domain in complex with promoters | 分子名称: | 1,2-ETHANEDIOL, Accessory gene regulator A, DNA (5'-D(*AP*CP*AP*GP*TP*TP*AP*AP*GP*AP*AP*T)-3'), ... | 著者 | Gopal, B, Rajasree, K. | 登録日 | 2015-01-19 | 公開日 | 2016-04-06 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Conformational features of theStaphylococcus aureusAgrA-promoter interactions rationalize quorum-sensing triggered gene expression. Biochem Biophys Rep, 6, 2016
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6GYS
| Cryo-EM structure of the CBF3-CEN3 complex of the budding yeast kinetochore | 分子名称: | Centromere DNA-binding protein complex CBF3 subunit A, Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, ... | 著者 | Yan, K, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D. | 登録日 | 2018-07-01 | 公開日 | 2018-12-05 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Architecture of the CBF3-centromere complex of the budding yeast kinetochore. Nat. Struct. Mol. Biol., 25, 2018
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1ZTA
| THE SOLUTION STRUCTURE OF A LEUCINE-ZIPPER MOTIF PEPTIDE | 分子名称: | LEUCINE ZIPPER MONOMER | 著者 | Saudek, V, Pastore, A, Castiglione Morelli, M.A, Frank, R, Gausepohl, H, Gibson, T. | 登録日 | 1990-10-11 | 公開日 | 1993-04-15 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The solution structure of a leucine-zipper motif peptide. Protein Eng., 4, 1991
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1POG
| SOLUTION STRUCTURE OF THE OCT-1 POU-HOMEO DOMAIN DETERMINED BY NMR AND RESTRAINED MOLECULAR DYNAMICS | 分子名称: | OCT-1 POU HOMEODOMAIN DNA-BINDING PROTEIN | 著者 | Cox, M, Van Tilborg, P.J.A, De Laat, W, Boelens, R, Van Leeuwen, H.C, Van Der Vliet, P.C, Kaptein, R. | 登録日 | 1994-10-12 | 公開日 | 1995-07-31 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the Oct-1 POU homeodomain determined by NMR and restrained molecular dynamics. J.Biomol.NMR, 6, 1995
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5A74
| Crystal structure of the homing endonuclease I-CvuI in complex with its target (Sro1.3) in the presence of 2 mM Mn | 分子名称: | 10MER DNA, 5'-D(*GP*AP*CP*GP*TP*TP*CP*TP*GP*AP)-3', 14MER DNA, ... | 著者 | Molina, R, Redondo, P, LopezMendez, B, Villate, M, Merino, N, Blanco, F.J, Valton, J, Grizot, S, Duchateau, P, Prieto, J, Montoya, G. | 登録日 | 2015-07-02 | 公開日 | 2015-09-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structure of the Homing Endonuclease I-Cvui Provides a New Template for Genome Modification J.Biol.Chem., 290, 2015
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3ZH9
| Bacillus subtilis DNA clamp loader delta protein (YqeN) | 分子名称: | DELTA, GLYCEROL, SULFATE ION | 著者 | Suwannachart, C, Sedelnikova, S, Soultanas, P, Oldham, N.J, Rafferty, J.B. | 登録日 | 2012-12-20 | 公開日 | 2013-04-03 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Insights Into the Structure and Assembly of the Bacillus Subtilis Clamp-Loader Complex and its Interaction with the Replicative Helicase. Nucleic Acids Res., 41, 2013
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4DLG
| Ternary Structure of the large Fragment of Taq DNA polymerase | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, ACETATE ION, DNA polymerase I, ... | 著者 | Marx, A, Diederichs, K, Obeid, S, Holzberger, B. | 登録日 | 2012-02-06 | 公開日 | 2012-11-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structural insights into the potential of 4-fluoroproline to modulate biophysical properties of protein Chem Sci, 3, 2012
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