1ZTA
THE SOLUTION STRUCTURE OF A LEUCINE-ZIPPER MOTIF PEPTIDE
Summary for 1ZTA
| Entry DOI | 10.2210/pdb1zta/pdb |
| Descriptor | LEUCINE ZIPPER MONOMER (1 entity in total) |
| Functional Keywords | dna-binding motif |
| Biological source | Saccharomyces cerevisiae (baker's yeast) |
| Cellular location | Nucleus: P03069 |
| Total number of polymer chains | 1 |
| Total formula weight | 4246.95 |
| Authors | Saudek, V.,Pastore, A.,Castiglione Morelli, M.A.,Frank, R.,Gausepohl, H.,Gibson, T. (deposition date: 1990-10-11, release date: 1993-04-15, Last modification date: 2024-05-22) |
| Primary citation | Saudek, V.,Pastore, A.,Morelli, M.A.,Frank, R.,Gausepohl, H.,Gibson, T. The solution structure of a leucine-zipper motif peptide. Protein Eng., 4:519-529, 1991 Cited by PubMed Abstract: We report the complete structure determination of a 34 residue synthetic peptide with the amino acid sequence of the dimerization domain (leucine zipper) of GCN4. A high resolution structure in solution was obtained by 1H-NMR studies and distance geometry calculations followed by restrained energy minimization. A set of 20 final structures was obtained with an average root mean square deviation of 1.3 A for the backbone atoms (excluding the first and the last two residues). The structure contains an uninterrupted helix. A comparison with a structure previously determined for a larger peptide containing both the DNA-binding region (basic region) and the leucine-zipper motif shows the structural independence of the leucine-zipper domain from the contiguous DNA binding region. PubMed: 1891459DOI: 10.1093/protein/4.5.519 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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