7VPX

The cryo-EM structure of the human pre-A complex

Summary for 7VPX

• Entry DOI: 10.2210/pdb7vpx/pdb
• EMDB information: 32074 32075 32076
• Descriptor: Splicing factor 3A subunit 2, Splicing factor 3A subunit 1, Splicing factor 3A subunit 3, ... (30 entities in total)
• Functional Keywords: human spliceosome, pre-a complex, prp5, a complex, u1 snrnp, u2 snrnp, splicing
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 35
• Total formula weight: 1405823.07

Authors

Zhang, X.,Zhan, X.,Shi, Y. (deposition date: 2021-10-18, release date: 2023-05-03)

• Primary citation: Zhang, X.,Zhan, X.,Shi, Y.; Mechanism for Branch Site Recognition and Proofreading During Prespliceosome Assembly; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3 Å)