Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7VPX

The cryo-EM structure of the human pre-A complex

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0000245	biological_process	spliceosomal complex assembly
1	0000375	biological_process	RNA splicing, via transesterification reactions
1	0000398	biological_process	mRNA splicing, via spliceosome
1	0000785	cellular_component	chromatin
1	0003723	molecular_function	RNA binding
1	0003729	molecular_function	mRNA binding
1	0005515	molecular_function	protein binding
1	0005634	cellular_component	nucleus
1	0005654	cellular_component	nucleoplasm
1	0005681	cellular_component	spliceosomal complex
1	0005684	cellular_component	U2-type spliceosomal complex
1	0005686	cellular_component	U2 snRNP
1	0005689	cellular_component	U12-type spliceosomal complex
1	0005730	cellular_component	nucleolus
1	0006338	biological_process	chromatin remodeling
1	0006397	biological_process	mRNA processing
1	0008380	biological_process	RNA splicing
1	0016607	cellular_component	nuclear speck
1	0031981	cellular_component	nuclear lumen
1	0034693	cellular_component	U11/U12 snRNP
1	0045943	biological_process	positive regulation of transcription by RNA polymerase I
1	0045944	biological_process	positive regulation of transcription by RNA polymerase II
1	0045945	biological_process	positive regulation of transcription by RNA polymerase III
1	0071004	cellular_component	U2-type prespliceosome
1	0071005	cellular_component	U2-type precatalytic spliceosome
1	0071013	cellular_component	catalytic step 2 spliceosome
1	0110016	cellular_component	B-WICH complex
1	1903241	biological_process	U2-type prespliceosome assembly
1	1990935	molecular_function	splicing factor binding
2	0000398	biological_process	mRNA splicing, via spliceosome
2	0003723	molecular_function	RNA binding
2	0005515	molecular_function	protein binding
2	0005634	cellular_component	nucleus
2	0005654	cellular_component	nucleoplasm
2	0005681	cellular_component	spliceosomal complex
2	0005684	cellular_component	U2-type spliceosomal complex
2	0005686	cellular_component	U2 snRNP
2	0005689	cellular_component	U12-type spliceosomal complex
2	0006397	biological_process	mRNA processing
2	0008380	biological_process	RNA splicing
2	0016607	cellular_component	nuclear speck
2	0071005	cellular_component	U2-type precatalytic spliceosome
2	0071011	cellular_component	precatalytic spliceosome
2	0071013	cellular_component	catalytic step 2 spliceosome
2	1903241	biological_process	U2-type prespliceosome assembly
3	0000124	cellular_component	SAGA complex
3	0000375	biological_process	RNA splicing, via transesterification reactions
3	0000398	biological_process	mRNA splicing, via spliceosome
3	0003676	molecular_function	nucleic acid binding
3	0005515	molecular_function	protein binding
3	0005634	cellular_component	nucleus
3	0005654	cellular_component	nucleoplasm
3	0005681	cellular_component	spliceosomal complex
3	0005684	cellular_component	U2-type spliceosomal complex
3	0005686	cellular_component	U2 snRNP
3	0005689	cellular_component	U12-type spliceosomal complex
3	0005730	cellular_component	nucleolus
3	0006282	biological_process	regulation of DNA repair
3	0006397	biological_process	mRNA processing
3	0008380	biological_process	RNA splicing
3	0030620	molecular_function	U2 snRNA binding
3	0042177	biological_process	negative regulation of protein catabolic process
3	0043484	biological_process	regulation of RNA splicing
3	0044877	molecular_function	protein-containing complex binding
3	0045893	biological_process	positive regulation of DNA-templated transcription
3	0071005	cellular_component	U2-type precatalytic spliceosome
3	0071013	cellular_component	catalytic step 2 spliceosome
3	1903241	biological_process	U2-type prespliceosome assembly
4	0000375	biological_process	RNA splicing, via transesterification reactions
4	0000398	biological_process	mRNA splicing, via spliceosome
4	0003676	molecular_function	nucleic acid binding
4	0003723	molecular_function	RNA binding
4	0005515	molecular_function	protein binding
4	0005634	cellular_component	nucleus
4	0005654	cellular_component	nucleoplasm
4	0005681	cellular_component	spliceosomal complex
4	0005684	cellular_component	U2-type spliceosomal complex
4	0005686	cellular_component	U2 snRNP
4	0005689	cellular_component	U12-type spliceosomal complex
4	0006397	biological_process	mRNA processing
4	0008380	biological_process	RNA splicing
4	0071005	cellular_component	U2-type precatalytic spliceosome
4	0071011	cellular_component	precatalytic spliceosome
4	1903241	biological_process	U2-type prespliceosome assembly
4	1990935	molecular_function	splicing factor binding
5	0000124	cellular_component	SAGA complex
5	0000398	biological_process	mRNA splicing, via spliceosome
5	0003723	molecular_function	RNA binding
5	0005515	molecular_function	protein binding
5	0005634	cellular_component	nucleus
5	0005654	cellular_component	nucleoplasm
5	0005681	cellular_component	spliceosomal complex
5	0005684	cellular_component	U2-type spliceosomal complex
5	0005686	cellular_component	U2 snRNP
5	0005689	cellular_component	U12-type spliceosomal complex
5	0006282	biological_process	regulation of DNA repair
5	0006397	biological_process	mRNA processing
5	0008380	biological_process	RNA splicing
5	0043484	biological_process	regulation of RNA splicing
5	0045893	biological_process	positive regulation of DNA-templated transcription
5	0071005	cellular_component	U2-type precatalytic spliceosome
5	0071011	cellular_component	precatalytic spliceosome
5	1903241	biological_process	U2-type prespliceosome assembly
5	1990935	molecular_function	splicing factor binding
6	0000398	biological_process	mRNA splicing, via spliceosome
6	0003677	molecular_function	DNA binding
6	0003723	molecular_function	RNA binding
6	0005515	molecular_function	protein binding
6	0005634	cellular_component	nucleus
6	0005654	cellular_component	nucleoplasm
6	0005681	cellular_component	spliceosomal complex
6	0005684	cellular_component	U2-type spliceosomal complex
6	0005686	cellular_component	U2 snRNP
6	0005689	cellular_component	U12-type spliceosomal complex
6	0006397	biological_process	mRNA processing
6	0008270	molecular_function	zinc ion binding
6	0008380	biological_process	RNA splicing
6	0016363	cellular_component	nuclear matrix
6	0016607	cellular_component	nuclear speck
6	0045893	biological_process	positive regulation of DNA-templated transcription
6	0046872	molecular_function	metal ion binding
6	0048863	biological_process	stem cell differentiation
6	0071005	cellular_component	U2-type precatalytic spliceosome
6	0071011	cellular_component	precatalytic spliceosome
6	1903241	biological_process	U2-type prespliceosome assembly
A	0000389	biological_process	mRNA 3'-splice site recognition
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005681	cellular_component	spliceosomal complex
A	0005684	cellular_component	U2-type spliceosomal complex
A	0005686	cellular_component	U2 snRNP
A	0006396	biological_process	RNA processing
A	0006397	biological_process	mRNA processing
A	0008380	biological_process	RNA splicing
A	0016607	cellular_component	nuclear speck
A	0045292	biological_process	mRNA cis splicing, via spliceosome
A	0071004	cellular_component	U2-type prespliceosome
A	0071005	cellular_component	U2-type precatalytic spliceosome
A	0071013	cellular_component	catalytic step 2 spliceosome
A	1903241	biological_process	U2-type prespliceosome assembly
B	0000245	biological_process	spliceosomal complex assembly
B	0000389	biological_process	mRNA 3'-splice site recognition
B	0000398	biological_process	mRNA splicing, via spliceosome
B	0003676	molecular_function	nucleic acid binding
B	0003723	molecular_function	RNA binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005681	cellular_component	spliceosomal complex
B	0005684	cellular_component	U2-type spliceosomal complex
B	0005686	cellular_component	U2 snRNP
B	0006397	biological_process	mRNA processing
B	0008270	molecular_function	zinc ion binding
B	0008380	biological_process	RNA splicing
B	0010976	biological_process	positive regulation of neuron projection development
B	0016607	cellular_component	nuclear speck
B	0046872	molecular_function	metal ion binding
B	0071004	cellular_component	U2-type prespliceosome
B	0071005	cellular_component	U2-type precatalytic spliceosome
B	0071013	cellular_component	catalytic step 2 spliceosome
B	1903241	biological_process	U2-type prespliceosome assembly
C	0000375	biological_process	RNA splicing, via transesterification reactions
C	0000389	biological_process	mRNA 3'-splice site recognition
C	0000398	biological_process	mRNA splicing, via spliceosome
C	0003676	molecular_function	nucleic acid binding
C	0003723	molecular_function	RNA binding
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005681	cellular_component	spliceosomal complex
C	0005684	cellular_component	U2-type spliceosomal complex
C	0005686	cellular_component	U2 snRNP
C	0006397	biological_process	mRNA processing
C	0008270	molecular_function	zinc ion binding
C	0008380	biological_process	RNA splicing
C	0016607	cellular_component	nuclear speck
C	0046872	molecular_function	metal ion binding
C	0071005	cellular_component	U2-type precatalytic spliceosome
C	0071013	cellular_component	catalytic step 2 spliceosome
C	1903241	biological_process	U2-type prespliceosome assembly
D	0000245	biological_process	spliceosomal complex assembly
D	0000389	biological_process	mRNA 3'-splice site recognition
D	0000398	biological_process	mRNA splicing, via spliceosome
D	0003676	molecular_function	nucleic acid binding
D	0003714	molecular_function	transcription corepressor activity
D	0003723	molecular_function	RNA binding
D	0003729	molecular_function	mRNA binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005681	cellular_component	spliceosomal complex
D	0005840	cellular_component	ribosome
D	0006397	biological_process	mRNA processing
D	0008270	molecular_function	zinc ion binding
D	0008380	biological_process	RNA splicing
D	0042802	molecular_function	identical protein binding
D	0045292	biological_process	mRNA cis splicing, via spliceosome
D	0045892	biological_process	negative regulation of DNA-templated transcription
D	0046872	molecular_function	metal ion binding
D	0048662	biological_process	negative regulation of smooth muscle cell proliferation
D	0080090	biological_process	regulation of primary metabolic process
D	0089701	cellular_component	U2AF complex
E	0000166	molecular_function	nucleotide binding
E	0000398	biological_process	mRNA splicing, via spliceosome
E	0001650	cellular_component	fibrillar center
E	0003676	molecular_function	nucleic acid binding
E	0003723	molecular_function	RNA binding
E	0003724	molecular_function	RNA helicase activity
E	0004386	molecular_function	helicase activity
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005681	cellular_component	spliceosomal complex
E	0005684	cellular_component	U2-type spliceosomal complex
E	0005686	cellular_component	U2 snRNP
E	0006397	biological_process	mRNA processing
E	0008380	biological_process	RNA splicing
E	0015030	cellular_component	Cajal body
E	0016607	cellular_component	nuclear speck
E	0016787	molecular_function	hydrolase activity
E	0016887	molecular_function	ATP hydrolysis activity
E	1903241	biological_process	U2-type prespliceosome assembly
F	0000398	biological_process	mRNA splicing, via spliceosome
F	0003723	molecular_function	RNA binding
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005681	cellular_component	spliceosomal complex
F	0005684	cellular_component	U2-type spliceosomal complex
F	0005686	cellular_component	U2 snRNP
F	0006397	biological_process	mRNA processing
F	0007283	biological_process	spermatogenesis
F	0008380	biological_process	RNA splicing
F	0016604	cellular_component	nuclear body
F	0016607	cellular_component	nuclear speck
F	0030532	cellular_component	small nuclear ribonucleoprotein complex
F	0030620	molecular_function	U2 snRNA binding
F	0071005	cellular_component	U2-type precatalytic spliceosome
F	0071007	cellular_component	U2-type catalytic step 2 spliceosome
F	0071013	cellular_component	catalytic step 2 spliceosome
F	1903241	biological_process	U2-type prespliceosome assembly
F	1990904	cellular_component	ribonucleoprotein complex
G	0000398	biological_process	mRNA splicing, via spliceosome
G	0001650	cellular_component	fibrillar center
G	0003676	molecular_function	nucleic acid binding
G	0003723	molecular_function	RNA binding
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005681	cellular_component	spliceosomal complex
G	0005684	cellular_component	U2-type spliceosomal complex
G	0005685	cellular_component	U1 snRNP
G	0005686	cellular_component	U2 snRNP
G	0006397	biological_process	mRNA processing
G	0008380	biological_process	RNA splicing
G	0016607	cellular_component	nuclear speck
G	0030619	molecular_function	U1 snRNA binding
G	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
G	0071005	cellular_component	U2-type precatalytic spliceosome
G	0071007	cellular_component	U2-type catalytic step 2 spliceosome
G	0071013	cellular_component	catalytic step 2 spliceosome
G	0097525	cellular_component	spliceosomal snRNP complex
G	1903241	biological_process	U2-type prespliceosome assembly
G	1990904	cellular_component	ribonucleoprotein complex
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005829	cellular_component	cytosol
J	0030544	molecular_function	Hsp70 protein binding
J	0045171	cellular_component	intercellular bridge
M	0000398	biological_process	mRNA splicing, via spliceosome
M	0003676	molecular_function	nucleic acid binding
M	0003677	molecular_function	DNA binding
M	0003723	molecular_function	RNA binding
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005681	cellular_component	spliceosomal complex
M	0005685	cellular_component	U1 snRNP
M	0006397	biological_process	mRNA processing
M	0008380	biological_process	RNA splicing
M	0030619	molecular_function	U1 snRNA binding
M	0042802	molecular_function	identical protein binding
M	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
M	0097525	cellular_component	spliceosomal snRNP complex
M	1990446	molecular_function	U1 snRNP binding
M	1990904	cellular_component	ribonucleoprotein complex
N	0000243	cellular_component	commitment complex
N	0000387	biological_process	spliceosomal snRNP assembly
N	0000395	biological_process	mRNA 5'-splice site recognition
N	0000398	biological_process	mRNA splicing, via spliceosome
N	0003676	molecular_function	nucleic acid binding
N	0003723	molecular_function	RNA binding
N	0003727	molecular_function	single-stranded RNA binding
N	0003729	molecular_function	mRNA binding
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005681	cellular_component	spliceosomal complex
N	0005685	cellular_component	U1 snRNP
N	0008270	molecular_function	zinc ion binding
N	0015030	cellular_component	Cajal body
N	0030619	molecular_function	U1 snRNA binding
N	0030627	molecular_function	pre-mRNA 5'-splice site binding
N	0042803	molecular_function	protein homodimerization activity
N	0046872	molecular_function	metal ion binding
N	0071004	cellular_component	U2-type prespliceosome
N	1990904	cellular_component	ribonucleoprotein complex
O	0000398	biological_process	mRNA splicing, via spliceosome
O	0003676	molecular_function	nucleic acid binding
O	0003723	molecular_function	RNA binding
O	0003729	molecular_function	mRNA binding
O	0005515	molecular_function	protein binding
O	0005634	cellular_component	nucleus
O	0005654	cellular_component	nucleoplasm
O	0005681	cellular_component	spliceosomal complex
O	0005685	cellular_component	U1 snRNP
O	0006397	biological_process	mRNA processing
O	0016607	cellular_component	nuclear speck
O	0030619	molecular_function	U1 snRNA binding
O	0043202	cellular_component	lysosomal lumen
O	0043484	biological_process	regulation of RNA splicing
O	0048026	biological_process	positive regulation of mRNA splicing, via spliceosome
O	0061084	biological_process	negative regulation of protein refolding
O	0071004	cellular_component	U2-type prespliceosome
O	0071300	biological_process	cellular response to retinoic acid
O	0071356	biological_process	cellular response to tumor necrosis factor
O	0071560	biological_process	cellular response to transforming growth factor beta stimulus
O	1904715	biological_process	negative regulation of chaperone-mediated autophagy
O	1990446	molecular_function	U1 snRNP binding
O	1990904	cellular_component	ribonucleoprotein complex
a	0000245	biological_process	spliceosomal complex assembly
a	0000387	biological_process	spliceosomal snRNP assembly
a	0000398	biological_process	mRNA splicing, via spliceosome
a	0003723	molecular_function	RNA binding
a	0005515	molecular_function	protein binding
a	0005634	cellular_component	nucleus
a	0005654	cellular_component	nucleoplasm
a	0005681	cellular_component	spliceosomal complex
a	0005682	cellular_component	U5 snRNP
a	0005684	cellular_component	U2-type spliceosomal complex
a	0005685	cellular_component	U1 snRNP
a	0005686	cellular_component	U2 snRNP
a	0005687	cellular_component	U4 snRNP
a	0005689	cellular_component	U12-type spliceosomal complex
a	0005737	cellular_component	cytoplasm
a	0005829	cellular_component	cytosol
a	0006397	biological_process	mRNA processing
a	0008380	biological_process	RNA splicing
a	0030532	cellular_component	small nuclear ribonucleoprotein complex
a	0034709	cellular_component	methylosome
a	0034715	cellular_component	pICln-Sm protein complex
a	0034719	cellular_component	SMN-Sm protein complex
a	0036261	biological_process	7-methylguanosine cap hypermethylation
a	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
a	0070062	cellular_component	extracellular exosome
a	0071005	cellular_component	U2-type precatalytic spliceosome
a	0071007	cellular_component	U2-type catalytic step 2 spliceosome
a	0071011	cellular_component	precatalytic spliceosome
a	0071013	cellular_component	catalytic step 2 spliceosome
a	0097525	cellular_component	spliceosomal snRNP complex
a	1903241	biological_process	U2-type prespliceosome assembly
a	1990904	cellular_component	ribonucleoprotein complex
b	0000387	biological_process	spliceosomal snRNP assembly
b	0000398	biological_process	mRNA splicing, via spliceosome
b	0003723	molecular_function	RNA binding
b	0005515	molecular_function	protein binding
b	0005634	cellular_component	nucleus
b	0005654	cellular_component	nucleoplasm
b	0005681	cellular_component	spliceosomal complex
b	0005682	cellular_component	U5 snRNP
b	0005683	cellular_component	U7 snRNP
b	0005684	cellular_component	U2-type spliceosomal complex
b	0005685	cellular_component	U1 snRNP
b	0005686	cellular_component	U2 snRNP
b	0005687	cellular_component	U4 snRNP
b	0005689	cellular_component	U12-type spliceosomal complex
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0006397	biological_process	mRNA processing
b	0008380	biological_process	RNA splicing
b	0022618	biological_process	protein-RNA complex assembly
b	0030532	cellular_component	small nuclear ribonucleoprotein complex
b	0034709	cellular_component	methylosome
b	0034715	cellular_component	pICln-Sm protein complex
b	0034719	cellular_component	SMN-Sm protein complex
b	0036261	biological_process	7-methylguanosine cap hypermethylation
b	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
b	0071005	cellular_component	U2-type precatalytic spliceosome
b	0071007	cellular_component	U2-type catalytic step 2 spliceosome
b	0071013	cellular_component	catalytic step 2 spliceosome
b	1903241	biological_process	U2-type prespliceosome assembly
b	1990904	cellular_component	ribonucleoprotein complex
c	0000245	biological_process	spliceosomal complex assembly
c	0000387	biological_process	spliceosomal snRNP assembly
c	0000398	biological_process	mRNA splicing, via spliceosome
c	0003723	molecular_function	RNA binding
c	0005515	molecular_function	protein binding
c	0005634	cellular_component	nucleus
c	0005654	cellular_component	nucleoplasm
c	0005681	cellular_component	spliceosomal complex
c	0005682	cellular_component	U5 snRNP
c	0005683	cellular_component	U7 snRNP
c	0005684	cellular_component	U2-type spliceosomal complex
c	0005685	cellular_component	U1 snRNP
c	0005686	cellular_component	U2 snRNP
c	0005687	cellular_component	U4 snRNP
c	0005689	cellular_component	U12-type spliceosomal complex
c	0005697	cellular_component	telomerase holoenzyme complex
c	0005737	cellular_component	cytoplasm
c	0005829	cellular_component	cytosol
c	0006397	biological_process	mRNA processing
c	0008380	biological_process	RNA splicing
c	0030532	cellular_component	small nuclear ribonucleoprotein complex
c	0034709	cellular_component	methylosome
c	0034715	cellular_component	pICln-Sm protein complex
c	0034719	cellular_component	SMN-Sm protein complex
c	0036261	biological_process	7-methylguanosine cap hypermethylation
c	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
c	0071005	cellular_component	U2-type precatalytic spliceosome
c	0071007	cellular_component	U2-type catalytic step 2 spliceosome
c	0071011	cellular_component	precatalytic spliceosome
c	0071013	cellular_component	catalytic step 2 spliceosome
c	1903241	biological_process	U2-type prespliceosome assembly
c	1990904	cellular_component	ribonucleoprotein complex
d	0000245	biological_process	spliceosomal complex assembly
d	0000387	biological_process	spliceosomal snRNP assembly
d	0000398	biological_process	mRNA splicing, via spliceosome
d	0003723	molecular_function	RNA binding
d	0005515	molecular_function	protein binding
d	0005634	cellular_component	nucleus
d	0005654	cellular_component	nucleoplasm
d	0005681	cellular_component	spliceosomal complex
d	0005682	cellular_component	U5 snRNP
d	0005683	cellular_component	U7 snRNP
d	0005684	cellular_component	U2-type spliceosomal complex
d	0005685	cellular_component	U1 snRNP
d	0005686	cellular_component	U2 snRNP
d	0005687	cellular_component	U4 snRNP
d	0005689	cellular_component	U12-type spliceosomal complex
d	0005737	cellular_component	cytoplasm
d	0005829	cellular_component	cytosol
d	0006397	biological_process	mRNA processing
d	0008380	biological_process	RNA splicing
d	0030532	cellular_component	small nuclear ribonucleoprotein complex
d	0034709	cellular_component	methylosome
d	0034719	cellular_component	SMN-Sm protein complex
d	0036261	biological_process	7-methylguanosine cap hypermethylation
d	0043186	cellular_component	P granule
d	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
d	0071004	cellular_component	U2-type prespliceosome
d	0071005	cellular_component	U2-type precatalytic spliceosome
d	0071007	cellular_component	U2-type catalytic step 2 spliceosome
d	0071011	cellular_component	precatalytic spliceosome
d	0071013	cellular_component	catalytic step 2 spliceosome
d	0097526	cellular_component	spliceosomal tri-snRNP complex
d	1903241	biological_process	U2-type prespliceosome assembly
d	1990904	cellular_component	ribonucleoprotein complex
e	0000243	cellular_component	commitment complex
e	0000387	biological_process	spliceosomal snRNP assembly
e	0000398	biological_process	mRNA splicing, via spliceosome
e	0003723	molecular_function	RNA binding
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0005654	cellular_component	nucleoplasm
e	0005681	cellular_component	spliceosomal complex
e	0005682	cellular_component	U5 snRNP
e	0005683	cellular_component	U7 snRNP
e	0005684	cellular_component	U2-type spliceosomal complex
e	0005685	cellular_component	U1 snRNP
e	0005686	cellular_component	U2 snRNP
e	0005687	cellular_component	U4 snRNP
e	0005689	cellular_component	U12-type spliceosomal complex
e	0005697	cellular_component	telomerase holoenzyme complex
e	0005737	cellular_component	cytoplasm
e	0005829	cellular_component	cytosol
e	0006396	biological_process	RNA processing
e	0006397	biological_process	mRNA processing
e	0006479	biological_process	protein methylation
e	0008380	biological_process	RNA splicing
e	0016604	cellular_component	nuclear body
e	0019899	molecular_function	enzyme binding
e	0030532	cellular_component	small nuclear ribonucleoprotein complex
e	0034709	cellular_component	methylosome
e	0034715	cellular_component	pICln-Sm protein complex
e	0034719	cellular_component	SMN-Sm protein complex
e	0036261	biological_process	7-methylguanosine cap hypermethylation
e	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
e	0070034	molecular_function	telomerase RNA binding
e	0071005	cellular_component	U2-type precatalytic spliceosome
e	0071007	cellular_component	U2-type catalytic step 2 spliceosome
e	0071011	cellular_component	precatalytic spliceosome
e	0071013	cellular_component	catalytic step 2 spliceosome
e	0071208	molecular_function	histone pre-mRNA DCP binding
e	0071209	molecular_function	U7 snRNA binding
e	0097526	cellular_component	spliceosomal tri-snRNP complex
e	1903241	biological_process	U2-type prespliceosome assembly
e	1990904	cellular_component	ribonucleoprotein complex
f	0000387	biological_process	spliceosomal snRNP assembly
f	0000398	biological_process	mRNA splicing, via spliceosome
f	0003723	molecular_function	RNA binding
f	0005515	molecular_function	protein binding
f	0005634	cellular_component	nucleus
f	0005654	cellular_component	nucleoplasm
f	0005681	cellular_component	spliceosomal complex
f	0005682	cellular_component	U5 snRNP
f	0005683	cellular_component	U7 snRNP
f	0005684	cellular_component	U2-type spliceosomal complex
f	0005685	cellular_component	U1 snRNP
f	0005686	cellular_component	U2 snRNP
f	0005687	cellular_component	U4 snRNP
f	0005689	cellular_component	U12-type spliceosomal complex
f	0005697	cellular_component	telomerase holoenzyme complex
f	0005737	cellular_component	cytoplasm
f	0005829	cellular_component	cytosol
f	0006397	biological_process	mRNA processing
f	0006479	biological_process	protein methylation
f	0008380	biological_process	RNA splicing
f	0030532	cellular_component	small nuclear ribonucleoprotein complex
f	0034709	cellular_component	methylosome
f	0034719	cellular_component	SMN-Sm protein complex
f	0036261	biological_process	7-methylguanosine cap hypermethylation
f	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
f	0070034	molecular_function	telomerase RNA binding
f	0070990	molecular_function	snRNP binding
f	0071004	cellular_component	U2-type prespliceosome
f	0071005	cellular_component	U2-type precatalytic spliceosome
f	0071007	cellular_component	U2-type catalytic step 2 spliceosome
f	0071013	cellular_component	catalytic step 2 spliceosome
f	0071204	cellular_component	histone pre-mRNA 3'end processing complex
f	0071208	molecular_function	histone pre-mRNA DCP binding
f	1903241	biological_process	U2-type prespliceosome assembly
f	1990446	molecular_function	U1 snRNP binding
f	1990447	molecular_function	U2 snRNP binding
f	1990904	cellular_component	ribonucleoprotein complex
g	0000243	cellular_component	commitment complex
g	0000245	biological_process	spliceosomal complex assembly
g	0000387	biological_process	spliceosomal snRNP assembly
g	0000398	biological_process	mRNA splicing, via spliceosome
g	0003723	molecular_function	RNA binding
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005654	cellular_component	nucleoplasm
g	0005681	cellular_component	spliceosomal complex
g	0005682	cellular_component	U5 snRNP
g	0005684	cellular_component	U2-type spliceosomal complex
g	0005685	cellular_component	U1 snRNP
g	0005686	cellular_component	U2 snRNP
g	0005687	cellular_component	U4 snRNP
g	0005689	cellular_component	U12-type spliceosomal complex
g	0005737	cellular_component	cytoplasm
g	0005829	cellular_component	cytosol
g	0006396	biological_process	RNA processing
g	0006397	biological_process	mRNA processing
g	0008380	biological_process	RNA splicing
g	0030532	cellular_component	small nuclear ribonucleoprotein complex
g	0034709	cellular_component	methylosome
g	0034715	cellular_component	pICln-Sm protein complex
g	0034719	cellular_component	SMN-Sm protein complex
g	0036261	biological_process	7-methylguanosine cap hypermethylation
g	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
g	0071005	cellular_component	U2-type precatalytic spliceosome
g	0071007	cellular_component	U2-type catalytic step 2 spliceosome
g	0071011	cellular_component	precatalytic spliceosome
g	0071013	cellular_component	catalytic step 2 spliceosome
g	0097526	cellular_component	spliceosomal tri-snRNP complex
g	1903241	biological_process	U2-type prespliceosome assembly
g	1990446	molecular_function	U1 snRNP binding
g	1990904	cellular_component	ribonucleoprotein complex
h	0000243	cellular_component	commitment complex
h	0000245	biological_process	spliceosomal complex assembly
h	0000387	biological_process	spliceosomal snRNP assembly
h	0000398	biological_process	mRNA splicing, via spliceosome
h	0003723	molecular_function	RNA binding
h	0005515	molecular_function	protein binding
h	0005634	cellular_component	nucleus
h	0005654	cellular_component	nucleoplasm
h	0005681	cellular_component	spliceosomal complex
h	0005682	cellular_component	U5 snRNP
h	0005684	cellular_component	U2-type spliceosomal complex
h	0005685	cellular_component	U1 snRNP
h	0005686	cellular_component	U2 snRNP
h	0005687	cellular_component	U4 snRNP
h	0005689	cellular_component	U12-type spliceosomal complex
h	0005737	cellular_component	cytoplasm
h	0005829	cellular_component	cytosol
h	0006396	biological_process	RNA processing
h	0006397	biological_process	mRNA processing
h	0008380	biological_process	RNA splicing
h	0030532	cellular_component	small nuclear ribonucleoprotein complex
h	0034709	cellular_component	methylosome
h	0034715	cellular_component	pICln-Sm protein complex
h	0034719	cellular_component	SMN-Sm protein complex
h	0036261	biological_process	7-methylguanosine cap hypermethylation
h	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
h	0071005	cellular_component	U2-type precatalytic spliceosome
h	0071007	cellular_component	U2-type catalytic step 2 spliceosome
h	0071011	cellular_component	precatalytic spliceosome
h	0071013	cellular_component	catalytic step 2 spliceosome
h	0097526	cellular_component	spliceosomal tri-snRNP complex
h	1903241	biological_process	U2-type prespliceosome assembly
h	1990446	molecular_function	U1 snRNP binding
h	1990904	cellular_component	ribonucleoprotein complex
i	0000245	biological_process	spliceosomal complex assembly
i	0000387	biological_process	spliceosomal snRNP assembly
i	0000398	biological_process	mRNA splicing, via spliceosome
i	0003723	molecular_function	RNA binding
i	0005515	molecular_function	protein binding
i	0005634	cellular_component	nucleus
i	0005654	cellular_component	nucleoplasm
i	0005681	cellular_component	spliceosomal complex
i	0005682	cellular_component	U5 snRNP
i	0005684	cellular_component	U2-type spliceosomal complex
i	0005685	cellular_component	U1 snRNP
i	0005686	cellular_component	U2 snRNP
i	0005687	cellular_component	U4 snRNP
i	0005689	cellular_component	U12-type spliceosomal complex
i	0005737	cellular_component	cytoplasm
i	0005829	cellular_component	cytosol
i	0006397	biological_process	mRNA processing
i	0008380	biological_process	RNA splicing
i	0030532	cellular_component	small nuclear ribonucleoprotein complex
i	0034709	cellular_component	methylosome
i	0034715	cellular_component	pICln-Sm protein complex
i	0034719	cellular_component	SMN-Sm protein complex
i	0036261	biological_process	7-methylguanosine cap hypermethylation
i	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
i	0070062	cellular_component	extracellular exosome
i	0071005	cellular_component	U2-type precatalytic spliceosome
i	0071007	cellular_component	U2-type catalytic step 2 spliceosome
i	0071011	cellular_component	precatalytic spliceosome
i	0071013	cellular_component	catalytic step 2 spliceosome
i	0097525	cellular_component	spliceosomal snRNP complex
i	1903241	biological_process	U2-type prespliceosome assembly
i	1990904	cellular_component	ribonucleoprotein complex
j	0000243	cellular_component	commitment complex
j	0000387	biological_process	spliceosomal snRNP assembly
j	0000398	biological_process	mRNA splicing, via spliceosome
j	0003723	molecular_function	RNA binding
j	0005515	molecular_function	protein binding
j	0005634	cellular_component	nucleus
j	0005654	cellular_component	nucleoplasm
j	0005681	cellular_component	spliceosomal complex
j	0005682	cellular_component	U5 snRNP
j	0005683	cellular_component	U7 snRNP
j	0005684	cellular_component	U2-type spliceosomal complex
j	0005685	cellular_component	U1 snRNP
j	0005686	cellular_component	U2 snRNP
j	0005687	cellular_component	U4 snRNP
j	0005689	cellular_component	U12-type spliceosomal complex
j	0005697	cellular_component	telomerase holoenzyme complex
j	0005737	cellular_component	cytoplasm
j	0005829	cellular_component	cytosol
j	0006396	biological_process	RNA processing
j	0006397	biological_process	mRNA processing
j	0006479	biological_process	protein methylation
j	0008380	biological_process	RNA splicing
j	0016604	cellular_component	nuclear body
j	0019899	molecular_function	enzyme binding
j	0030532	cellular_component	small nuclear ribonucleoprotein complex
j	0034709	cellular_component	methylosome
j	0034715	cellular_component	pICln-Sm protein complex
j	0034719	cellular_component	SMN-Sm protein complex
j	0036261	biological_process	7-methylguanosine cap hypermethylation
j	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
j	0070034	molecular_function	telomerase RNA binding
j	0071005	cellular_component	U2-type precatalytic spliceosome
j	0071007	cellular_component	U2-type catalytic step 2 spliceosome
j	0071011	cellular_component	precatalytic spliceosome
j	0071013	cellular_component	catalytic step 2 spliceosome
j	0071208	molecular_function	histone pre-mRNA DCP binding
j	0071209	molecular_function	U7 snRNA binding
j	0097526	cellular_component	spliceosomal tri-snRNP complex
j	1903241	biological_process	U2-type prespliceosome assembly
j	1990904	cellular_component	ribonucleoprotein complex
k	0000387	biological_process	spliceosomal snRNP assembly
k	0000398	biological_process	mRNA splicing, via spliceosome
k	0003723	molecular_function	RNA binding
k	0005515	molecular_function	protein binding
k	0005634	cellular_component	nucleus
k	0005654	cellular_component	nucleoplasm
k	0005681	cellular_component	spliceosomal complex
k	0005682	cellular_component	U5 snRNP
k	0005683	cellular_component	U7 snRNP
k	0005684	cellular_component	U2-type spliceosomal complex
k	0005685	cellular_component	U1 snRNP
k	0005686	cellular_component	U2 snRNP
k	0005687	cellular_component	U4 snRNP
k	0005689	cellular_component	U12-type spliceosomal complex
k	0005697	cellular_component	telomerase holoenzyme complex
k	0005737	cellular_component	cytoplasm
k	0005829	cellular_component	cytosol
k	0006397	biological_process	mRNA processing
k	0006479	biological_process	protein methylation
k	0008380	biological_process	RNA splicing
k	0030532	cellular_component	small nuclear ribonucleoprotein complex
k	0034709	cellular_component	methylosome
k	0034719	cellular_component	SMN-Sm protein complex
k	0036261	biological_process	7-methylguanosine cap hypermethylation
k	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
k	0070034	molecular_function	telomerase RNA binding
k	0070990	molecular_function	snRNP binding
k	0071004	cellular_component	U2-type prespliceosome
k	0071005	cellular_component	U2-type precatalytic spliceosome
k	0071007	cellular_component	U2-type catalytic step 2 spliceosome
k	0071013	cellular_component	catalytic step 2 spliceosome
k	0071204	cellular_component	histone pre-mRNA 3'end processing complex
k	0071208	molecular_function	histone pre-mRNA DCP binding
k	1903241	biological_process	U2-type prespliceosome assembly
k	1990446	molecular_function	U1 snRNP binding
k	1990447	molecular_function	U2 snRNP binding
k	1990904	cellular_component	ribonucleoprotein complex
l	0000245	biological_process	spliceosomal complex assembly
l	0000387	biological_process	spliceosomal snRNP assembly
l	0000398	biological_process	mRNA splicing, via spliceosome
l	0003723	molecular_function	RNA binding
l	0005515	molecular_function	protein binding
l	0005634	cellular_component	nucleus
l	0005654	cellular_component	nucleoplasm
l	0005681	cellular_component	spliceosomal complex
l	0005682	cellular_component	U5 snRNP
l	0005683	cellular_component	U7 snRNP
l	0005684	cellular_component	U2-type spliceosomal complex
l	0005685	cellular_component	U1 snRNP
l	0005686	cellular_component	U2 snRNP
l	0005687	cellular_component	U4 snRNP
l	0005689	cellular_component	U12-type spliceosomal complex
l	0005697	cellular_component	telomerase holoenzyme complex
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0006397	biological_process	mRNA processing
l	0008380	biological_process	RNA splicing
l	0030532	cellular_component	small nuclear ribonucleoprotein complex
l	0034709	cellular_component	methylosome
l	0034715	cellular_component	pICln-Sm protein complex
l	0034719	cellular_component	SMN-Sm protein complex
l	0036261	biological_process	7-methylguanosine cap hypermethylation
l	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
l	0071005	cellular_component	U2-type precatalytic spliceosome
l	0071007	cellular_component	U2-type catalytic step 2 spliceosome
l	0071011	cellular_component	precatalytic spliceosome
l	0071013	cellular_component	catalytic step 2 spliceosome
l	1903241	biological_process	U2-type prespliceosome assembly
l	1990904	cellular_component	ribonucleoprotein complex
m	0000387	biological_process	spliceosomal snRNP assembly
m	0000398	biological_process	mRNA splicing, via spliceosome
m	0003723	molecular_function	RNA binding
m	0005515	molecular_function	protein binding
m	0005634	cellular_component	nucleus
m	0005654	cellular_component	nucleoplasm
m	0005681	cellular_component	spliceosomal complex
m	0005682	cellular_component	U5 snRNP
m	0005683	cellular_component	U7 snRNP
m	0005684	cellular_component	U2-type spliceosomal complex
m	0005685	cellular_component	U1 snRNP
m	0005686	cellular_component	U2 snRNP
m	0005687	cellular_component	U4 snRNP
m	0005689	cellular_component	U12-type spliceosomal complex
m	0005737	cellular_component	cytoplasm
m	0005829	cellular_component	cytosol
m	0006397	biological_process	mRNA processing
m	0008380	biological_process	RNA splicing
m	0022618	biological_process	protein-RNA complex assembly
m	0030532	cellular_component	small nuclear ribonucleoprotein complex
m	0034709	cellular_component	methylosome
m	0034715	cellular_component	pICln-Sm protein complex
m	0034719	cellular_component	SMN-Sm protein complex
m	0036261	biological_process	7-methylguanosine cap hypermethylation
m	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
m	0071005	cellular_component	U2-type precatalytic spliceosome
m	0071007	cellular_component	U2-type catalytic step 2 spliceosome
m	0071013	cellular_component	catalytic step 2 spliceosome
m	1903241	biological_process	U2-type prespliceosome assembly
m	1990904	cellular_component	ribonucleoprotein complex
n	0000245	biological_process	spliceosomal complex assembly
n	0000387	biological_process	spliceosomal snRNP assembly
n	0000398	biological_process	mRNA splicing, via spliceosome
n	0003723	molecular_function	RNA binding
n	0005515	molecular_function	protein binding
n	0005634	cellular_component	nucleus
n	0005654	cellular_component	nucleoplasm
n	0005681	cellular_component	spliceosomal complex
n	0005682	cellular_component	U5 snRNP
n	0005683	cellular_component	U7 snRNP
n	0005684	cellular_component	U2-type spliceosomal complex
n	0005685	cellular_component	U1 snRNP
n	0005686	cellular_component	U2 snRNP
n	0005687	cellular_component	U4 snRNP
n	0005689	cellular_component	U12-type spliceosomal complex
n	0005737	cellular_component	cytoplasm
n	0005829	cellular_component	cytosol
n	0006397	biological_process	mRNA processing
n	0008380	biological_process	RNA splicing
n	0030532	cellular_component	small nuclear ribonucleoprotein complex
n	0034709	cellular_component	methylosome
n	0034719	cellular_component	SMN-Sm protein complex
n	0036261	biological_process	7-methylguanosine cap hypermethylation
n	0043186	cellular_component	P granule
n	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
n	0071004	cellular_component	U2-type prespliceosome
n	0071005	cellular_component	U2-type precatalytic spliceosome
n	0071007	cellular_component	U2-type catalytic step 2 spliceosome
n	0071011	cellular_component	precatalytic spliceosome
n	0071013	cellular_component	catalytic step 2 spliceosome
n	0097526	cellular_component	spliceosomal tri-snRNP complex
n	1903241	biological_process	U2-type prespliceosome assembly
n	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00039
Number of Residues	9
Details	DEAD_ATP_HELICASE DEAD-box subfamily ATP-dependent helicases signature. VLDEADRmF

Chain	Residue	Details
E	VAL527-PHE535

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. FVCSATH

Chain	Residue	Details
3	PHE287-HIS293

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	SITE: Interaction with RNA => ECO:0000269\|PubMed:27720643

Chain	Residue	Details
5	TYR5
6	CYS72
6	CYS75
6	CYS85
5	GLY20
3	GLU352
3	ARG429
3	ASN916
6	CYS46
6	CYS49
6	CYS58
6	CYS61

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N-acetylthreonine => ECO:0007744\|PubMed:19413330

Chain	Residue	Details
5	THR2
3	LYS1171

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:17525332

Chain	Residue	Details
5	SER9
1	CYS677
1	GLU1205

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0007744\|PubMed:19608861

Chain	Residue	Details
5	LYS17
1	THR235
1	THR426
i	LYS6
i	LYS8

site_id	SWS_FT_FI5
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
2	SER307
2	SER309
C	SER369

site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
2	THR311
1	LYS554
1	LYS562

site_id	SWS_FT_FI7
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:23186163

Chain	Residue	Details
2	SER317
2	SER861

site_id	SWS_FT_FI8
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:19690332

Chain	Residue	Details
2	SER360
2	SER362

site_id	SWS_FT_FI9
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:18318008, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
2	SER431
2	SER435
2	SER436

site_id	SWS_FT_FI10
Number of Residues	1
Details	MOD_RES: Symmetric dimethylarginine; by PRMT9; alternate => ECO:0000269\|PubMed:25737013

Chain	Residue	Details
2	ARG508
A	LYS131
A	LYS424
A	LYS499

site_id	SWS_FT_FI11
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
2	THR780
E	LYS325
E	LYS779
E	LYS907
E	LYS915

site_id	SWS_FT_FI12
Number of Residues	9
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:28112733

Chain	Residue	Details
2	LYS10
2	LYS280
2	LYS492
2	LYS543
2	LYS770
2	LYS790
2	LYS843
2	LYS857

site_id	SWS_FT_FI13
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:25755297, ECO:0007744\|PubMed:25772364, ECO:0007744\|PubMed:28112733

Chain	Residue	Details
2	LYS400

site_id	SWS_FT_FI14
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:25218447, ECO:0007744\|PubMed:28112733

Chain	Residue	Details
2	LYS412

site_id	SWS_FT_FI15
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
1	THR227

site_id	SWS_FT_FI16
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250\|UniProtKB:Q99NB9

Chain	Residue	Details
1	SER229

site_id	SWS_FT_FI17
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000269\|PubMed:12105215

Chain	Residue	Details
1	THR244

site_id	SWS_FT_FI18
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000305\|PubMed:12105215

Chain	Residue	Details
1	THR248

site_id	SWS_FT_FI19
Number of Residues	5
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
1	THR257
1	THR261
1	THR278
1	THR303
1	THR313

site_id	SWS_FT_FI20
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18220336, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
1	THR267

site_id	SWS_FT_FI21
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:24275569

Chain	Residue	Details
1	THR273

site_id	SWS_FT_FI22
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:24275569

Chain	Residue	Details
1	SER287

site_id	SWS_FT_FI23
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
1	THR296

site_id	SWS_FT_FI24
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:17081983

Chain	Residue	Details
1	THR299

site_id	SWS_FT_FI25
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:23186163

Chain	Residue	Details
1	SER322

site_id	SWS_FT_FI26
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
1	THR326

site_id	SWS_FT_FI27
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:16964243, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:20068231

Chain	Residue	Details
1	THR328

site_id	SWS_FT_FI28
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
1	SER332

site_id	SWS_FT_FI29
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:21406692

Chain	Residue	Details
1	THR341

site_id	SWS_FT_FI30
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:21406692

Chain	Residue	Details
1	SER344

site_id	SWS_FT_FI31
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:21406692

Chain	Residue	Details
1	SER349

site_id	SWS_FT_FI32
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
1	THR350
1	THR436

site_id	SWS_FT_FI33
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18691976, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
1	THR354

site_id	SWS_FT_FI34
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
1	SER400

site_id	SWS_FT_FI35
Number of Residues	1
Details	MOD_RES: Phosphothreonine; by DYRK1A => ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
1	THR434

site_id	SWS_FT_FI36
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
1	SER488

site_id	SWS_FT_FI37
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744\|PubMed:28112733

Chain	Residue	Details
1	LYS214

site_id	SWS_FT_FI38
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:28112733

Chain	Residue	Details
1	LYS430

site_id	SWS_FT_FI39
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744\|PubMed:25114211, ECO:0007744\|PubMed:25218447, ECO:0007744\|PubMed:25755297, ECO:0007744\|PubMed:28112733

Chain	Residue	Details
1	LYS413

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)