7YI2

Cryo-EM structure of Rpd3S in loose-state Rpd3S-NCP complex

Summary for 7YI2

• Entry DOI: 10.2210/pdb7yi2/pdb
• Related: 7YI0 7YI1
• EMDB information: 33845 33848 33849
• Descriptor: Wisdom 601 DNA (167-MER), Transcriptional regulatory protein SIN3, Histone deacetylase RPD3, ... (7 entities in total)
• Functional Keywords: dynamic histone modifications, gene regulation, histone deacetylase complex
• Biological source: synthetic construct; More
• Total number of polymer chains: 7
• Total formula weight: 530611.97

Authors

Li, H.T.,Yan, C.Y.,Guan, H.P.,Wang, P. (deposition date: 2022-07-14, release date: 2023-06-14, Last modification date: 2023-08-30)

• Primary citation: Guan, H.,Wang, P.,Zhang, P.,Ruan, C.,Ou, Y.,Peng, B.,Zheng, X.,Lei, J.,Li, B.,Yan, C.,Li, H.; Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S.; Nature, 620:669-675, 2023; PubMed: 37468628; DOI: 10.1038/s41586-023-06349-1

Experimental method

ELECTRON MICROSCOPY (3.4 Å)