7YI4

Cryo-EM structure of Rpd3S complex bound to H3K36me3 nucleosome in close state

This is a non-PDB format compatible entry.

Summary for 7YI4

• Entry DOI: 10.2210/pdb7yi4/pdb
• Related: 7YI1 7YI3
• EMDB information: 33848 33850 33851
• Descriptor: Transcriptional regulatory protein SIN3, Histone H3, ZINC ION, ... (11 entities in total)
• Functional Keywords: dynamic histone modifications, gene regulation, histone deacetylase complex
• Biological source: Saccharomyces cerevisiae S288C (baker's yeast); More
• Total number of polymer chains: 16
• Total formula weight: 684102.85

Authors

Li, H.T.,Yan, C.Y.,Guan, H.P.,Wang, P. (deposition date: 2022-07-14, release date: 2023-06-14, Last modification date: 2023-08-30)

• Primary citation: Guan, H.,Wang, P.,Zhang, P.,Ruan, C.,Ou, Y.,Peng, B.,Zheng, X.,Lei, J.,Li, B.,Yan, C.,Li, H.; Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S.; Nature, 620:669-675, 2023; PubMed: 37468628; DOI: 10.1038/s41586-023-06349-1

Experimental method

ELECTRON MICROSCOPY (3.96 Å)