PDB: 1911 件ウェブページステータス検索Chemie searchBIRD

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4Y7R	Crystal structure of WDR5 in complex with MYC MbIIIb peptide 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MYC MbIIIb peptide, ... 著者 Sun, Q, Phan, J, Olejniczak, E.T, Thomas, L.R, Fesik, S.W, Tansey, W.P. 登録日 2015-02-16 公開日 2015-04-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.898 Å) 主引用文献 Interaction with WDR5 Promotes Target Gene Recognition and Tumorigenesis by MYC. Mol.Cell, 58, 2015
8DWJ	Primase of mutant bacteriophage T4 primosome with single strand DNA/RNA primer hybrid in primer exiting state 分子名称: DNA (70-MER), DNA primase, RNA(5'-ppp-GCCGA-3'), ... 著者 Feng, X, Li, H. 登録日 2022-08-01 公開日 2023-06-14 最終更新日 2023-08-23 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis of the T4 bacteriophage primosome assembly and primer synthesis. Nat Commun, 14, 2023
2RS3	STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES 分子名称: 5-(7-(5-HYDRO-4-ETHYL-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ... 著者 Badger, J, Smith, T.J, Rossmann, M.G. 登録日 1988-10-03 公開日 1990-01-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses. Proteins, 6, 1989
8AVE	Human leptin in complex with the human LEP-R ectodomain fused to a C-terminal trimeric isoleucine GCN4 zipper (2:2 model) 分子名称: Leptin, Leptin receptor 著者 Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A. 登録日 2022-08-26 公開日 2023-04-05 最終更新日 2023-04-26 実験手法 ELECTRON MICROSCOPY (5.62 Å) 主引用文献 Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
6S1C	P3221 crystal form of the Ctf18-1-8/Pol2(1-528) complex 分子名称: Chromosome transmission fidelity protein 18, Chromosome transmission fidelity protein 8, DNA polymerase epsilon catalytic subunit A, ... 著者 Grabarczyk, D.B. 登録日 2019-06-18 公開日 2020-07-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (6.1 Å) 主引用文献 Ctf18-RFC and DNA Pol ε form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication. Nucleic Acids Res., 48, 2020
6MEV	Structure of JMJD6 bound to Mono-Methyl Arginine. 分子名称: (2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]pentanoic acid, 2-OXOGLUTARIC ACID, Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, ... 著者 Lee, S, Zhang, G. 登録日 2018-09-07 公開日 2019-09-18 最終更新日 2020-04-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes. Elife, 9, 2020
5VIC	Crystal structure of anti-Zika antibody Z004 bound to DENV-1 Envelope protein DIII 分子名称: Dengue 1 Envelope DIII domain, Fab heavy chain, Fab light chain 著者 Keeffe, J.R, West Jr, A.P, Gristick, H.B, Bjorkman, P.J. 登録日 2017-04-14 公開日 2017-05-03 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico. Cell, 169, 2017
5VNY	Crystal structure of DM14-3 domain of Lgd 分子名称: Lethal (2) giant discs 1, isoform B 著者 McMillan, B.J, Blacklow, S.C. 登録日 2017-05-01 公開日 2017-06-14 実験手法 X-RAY DIFFRACTION (1.101 Å) 主引用文献 Structural Basis for Regulation of ESCRT-III Complexes by Lgd. Cell Rep, 19, 2017
4LMO	Structure of a vertebrate RNA binding domain of telomerase (TRBD) 分子名称: Telomerase reverse transcriptase 著者 Harkisheimer, M, Mason, M, Shuvaeva, E, Skordalakes, E. 登録日 2013-07-10 公開日 2013-10-09 最終更新日 2013-10-30 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 A Motif in the Vertebrate Telomerase N-Terminal Linker of TERT Contributes to RNA Binding and Telomerase Activity and Processivity. Structure, 21, 2013
2OJ3	Hepatitis Delta Virus ribozyme precursor structure, with C75U mutation, bound to Tl+ and cobalt hexammine (Co(NH3)63+) 分子名称: COBALT HEXAMMINE(III), HDV RIBOZYME, THALLIUM (I) ION, ... 著者 Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A. 登録日 2007-01-12 公開日 2007-03-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural roles of monovalent cations in the HDV ribozyme. Structure, 15, 2007
7Z3Q	Crystal structure of the human leptin:LepR-CRH2 encounter complex to 3.6 A resolution. 分子名称: Leptin, Leptin receptor 著者 Verstraete, K, Verschueren, K, Alexandra, T, Savvides, S.N. 登録日 2022-03-02 公開日 2023-03-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.617 Å) 主引用文献 Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
1EAM	VACCINIA METHYLTRANSFERASE VP39 MUTANT (EC: 2.7.7.19) 分子名称: PROTEIN (VP39), S-ADENOSYL-L-HOMOCYSTEINE 著者 Hu, G, Hodel, A.E, Gershon, P.D, Quiocho, F.A. 登録日 1999-01-26 公開日 1999-06-14 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains. Proc.Natl.Acad.Sci.USA, 96, 1999
8AVO	Human leptin in complex with the human LEP-R ectodomain fused to a C-terminal trimeric isoleucine GCN4 zipper (open 3:3 model). 分子名称: Leptin, Leptin receptor 著者 Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A. 登録日 2022-08-26 公開日 2023-04-05 最終更新日 2023-04-26 実験手法 ELECTRON MICROSCOPY (6.84 Å) 主引用文献 Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
8AVF	Human leptin in complex with the human LEP-R ectodomain fused to a C-terminal trimeric isoleucine GCN4 zipper (closed 3:3 model) 分子名称: Leptin, Leptin receptor 著者 Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A. 登録日 2022-08-26 公開日 2023-04-05 最終更新日 2023-04-26 実験手法 ELECTRON MICROSCOPY (6.45 Å) 主引用文献 Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
1R2P	Solution structure of domain 5 from the ai5(gamma) group II intron 分子名称: 34-MER 著者 Sigel, R.K.O, Sashital, D.G, Abramovitz, D.L, Palmer III, A.G, Butcher, S.E, Pyle, A.M. 登録日 2003-09-29 公開日 2004-02-03 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of domain 5 of a group II intron ribozyme reveals a new RNA motif. Nat.Struct.Mol.Biol., 11, 2004
2P5P	Crystal Structure Analysis of the West Nile virus envelope (E) protein domain III 分子名称: Genome polyprotein 著者 Gao, F, Yuan, F, Gao, G.F. 登録日 2007-03-16 公開日 2008-03-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal Structure Analysis of the West Nile virus envelope (E) protein domain III To be Published
4II5	Structure of PCDK2/CYCLINA bound to ADP and 1 MAGNESIUM ION 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cyclin-A2, Cyclin-dependent kinase 2, ... 著者 Jacobsen, D.M, Bao, Z.-Q, O'Brien, P.J, Brooks III, C.L, Young, M.A. 登録日 2012-12-19 公開日 2013-01-23 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Price to be paid for two-metal catalysis: Magnesium ions that accelerate chemistry unavoidably limit product release from a PROTEIN KINASE J.Am.Chem.Soc., 134, 2012
7Z3P	Crystal structure of the mouse leptin:LepR-CRH2 encounter complex to 1.95 A resolution. 分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, Leptin, ... 著者 Tsirigotaki, A, Verschueren, K, Savvides, S.N, Verstraete, K. 登録日 2022-03-02 公開日 2023-03-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.943 Å) 主引用文献 Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
5NAS	Crystal structure of human 14-3-3 zeta in complex with PI4KIIIB peptide 分子名称: 14-3-3 protein zeta/delta, Phosphatidylinositol 4-kinase beta 著者 Boura, E, Eisenreichova, A. 登録日 2017-02-28 公開日 2017-03-29 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Crystal structure of human 14-3-3 zeta in complex with PI4KIIIB peptide To Be Published
3RB9	Crystal structure of the M. tuberculosis beta clamp 分子名称: DNA polymerase III subunit beta 著者 Kukshal, V, Ramachandran, R. 登録日 2011-03-29 公開日 2012-04-04 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 M. tuberculosis Sliding beta-Clamp Does Not Interact Directly with the NAD(+)-Dependent DNA Ligase Plos One, 7, 2012
7CMW	Complex structure of PARP1 catalytic domain with pamiparib 分子名称: (2R)-14-fluoro-2-methyl-6,9,10,19-tetrazapentacyclo[14.2.1.02,6.08,18.012,17]nonadeca-1(18),8,12(17),13,15-pentaen-11-one, GLYCEROL, Poly [ADP-ribose] polymerase 1 著者 Feng, Y.C, Peng, H, Hong, Y, Liu, Y. 登録日 2020-07-29 公開日 2020-12-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Discovery of Pamiparib (BGB-290), a Potent and Selective Poly (ADP-ribose) Polymerase (PARP) Inhibitor in Clinical Development. J.Med.Chem., 63, 2020
1R08	STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES 分子名称: 5-(5-(2,6-DICHLORO-4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)PENTYL)-3-(HYDROXYETHYL OXYMETHYLENEOXYMETHYL) ISOXAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ... 著者 Badger, J, Smith, T.J, Rossmann, M.G. 登録日 1988-10-03 公開日 1990-01-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses. Proteins, 6, 1989
9FMD	Integrative model of the human post-catalytic spliceosome (P-complex) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... 著者 Rothe, P, Plaschka, C, Vorlaender, M.K. 登録日 2024-06-05 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Mechanism for the initiation of spliceosome disassembly. Nature, 2024
8C6J	Human spliceosomal PM5 C* complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... 著者 Dybkov, O, Kastner, B, Luehrmann, R. 登録日 2023-01-12 公開日 2023-07-12 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Regulation of 3' splice site selection after step 1 of splicing by spliceosomal C* proteins. Sci Adv, 9, 2023
7W59	The cryo-EM structure of human pre-C*-I complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2021-11-29 公開日 2022-06-22 最終更新日 2022-08-17 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022

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