6S1C
P3221 crystal form of the Ctf18-1-8/Pol2(1-528) complex
Summary for 6S1C
Entry DOI | 10.2210/pdb6s1c/pdb |
Descriptor | DNA polymerase epsilon catalytic subunit A, Sister chromatid cohesion protein DCC1, Chromosome transmission fidelity protein 8, ... (4 entities in total) |
Functional Keywords | dna polymerase, pcna loader, protein complex, replication |
Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More |
Total number of polymer chains | 8 |
Total formula weight | 251398.10 |
Authors | Grabarczyk, D.B. (deposition date: 2019-06-18, release date: 2020-07-08, Last modification date: 2024-01-24) |
Primary citation | Stokes, K.,Winczura, A.,Song, B.,Piccoli, G.,Grabarczyk, D.B. Ctf18-RFC and DNA Pol ε form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication. Nucleic Acids Res., 48:8128-8145, 2020 Cited by PubMed: 32585006DOI: 10.1093/nar/gkaa541 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (6.1 Å) |
Structure validation
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