6S1C
P3221 crystal form of the Ctf18-1-8/Pol2(1-528) complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, E | DNA polymerase epsilon catalytic subunit A | polymer | 549 | 62516.3 | 2 | UniProt (P21951) Pfam (PF03104) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | DNA polymerase II subunit A |
2 | B, F | Sister chromatid cohesion protein DCC1 | polymer | 380 | 44133.8 | 2 | UniProt (P25559) Pfam (PF09724) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Defective in sister chromatid cohesion protein 1 |
3 | C, G | Chromosome transmission fidelity protein 8 | polymer | 133 | 15189.7 | 2 | UniProt (P38877) Pfam (PF09696) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | |
4 | D, H | Chromosome transmission fidelity protein 18 | polymer | 33 | 3859.3 | 2 | UniProt (P49956) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Sequence modifications
A, E: 1 - 524 (UniProt: P21951)
D, H: 713 - 741 (UniProt: P49956)
PDB | External Database | Details |
---|---|---|
Met -24 | - | initiating methionine |
Lys -23 | - | expression tag |
His -22 | - | expression tag |
His -21 | - | expression tag |
His -20 | - | expression tag |
His -19 | - | expression tag |
His -18 | - | expression tag |
His -17 | - | expression tag |
Ser -16 | - | expression tag |
Ala -15 | - | expression tag |
Gly -14 | - | expression tag |
Leu -13 | - | expression tag |
Glu -12 | - | expression tag |
Val -11 | - | expression tag |
Leu -10 | - | expression tag |
Phe -9 | - | expression tag |
Gln -8 | - | expression tag |
Gly -7 | - | expression tag |
Pro -6 | - | expression tag |
Gly -5 | - | expression tag |
Thr -4 | - | expression tag |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
Glu -1 | - | expression tag |
Phe 0 | - | expression tag |
Ala 290 | Asp 290 | engineered mutation |
Ala 292 | Glu 292 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 709 | - | expression tag |
Ala 710 | - | expression tag |
Met 711 | - | expression tag |
Gly 712 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 251398.1 | |
All* | Total formula weight | 251398.1 |