7W59

The cryo-EM structure of human pre-C*-I complex

Summary for 7W59

• Entry DOI: 10.2210/pdb7w59/pdb
• EMDB information: 32317
• Descriptor: Pre-mRNA-processing-splicing factor 8, Pre-mRNA-splicing factor RBM22, Spliceosome-associated protein CWC15 homolog, ... (45 entities in total)
• Functional Keywords: spliceosome, c* complex, rna splicing, prp22, exon ligation, fam192a, splicing
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 50
• Total formula weight: 2672892.16

Authors

Zhan, X.,Lu, Y.,Shi, Y. (deposition date: 2021-11-29, release date: 2022-06-22, Last modification date: 2022-08-17)

• Primary citation: Zhan, X.,Lu, Y.,Zhang, X.,Yan, C.,Shi, Y.; Mechanism of exon ligation by human spliceosome.; Mol.Cell, 82:2769-2778.e4, 2022; PubMed: 35705093; DOI: 10.1016/j.molcel.2022.05.021

Experimental method

ELECTRON MICROSCOPY (3.6 Å)