6MEV
Structure of JMJD6 bound to Mono-Methyl Arginine.
Summary for 6MEV
Entry DOI | 10.2210/pdb6mev/pdb |
Descriptor | Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, 2-OXOGLUTARIC ACID, FE (III) ION, ... (5 entities in total) |
Functional Keywords | jumonji, arginine, transcription, methyl, endopeptidase, exopeptidase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 8 |
Total formula weight | 322923.49 |
Authors | |
Primary citation | Lee, S.,Liu, H.,Hill, R.,Chen, C.,Hong, X.,Crawford, F.,Kingsley, M.,Zhang, Q.,Liu, X.,Chen, Z.,Lengeling, A.,Bernt, K.M.,Marrack, P.,Kappler, J.,Zhou, Q.,Li, C.Y.,Xue, Y.,Hansen, K.,Zhang, G. JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes. Elife, 9:-, 2020 Cited by PubMed: 32048991DOI: 10.7554/eLife.53930 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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