6MEV
Structure of JMJD6 bound to Mono-Methyl Arginine.
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue NMM A 403 |
| Chain | Residue |
| A | PHE133 |
| A | HOH570 |
| A | THR184 |
| A | GLY185 |
| A | ILE186 |
| A | HIS187 |
| A | ASP189 |
| A | ASP230 |
| A | HIS273 |
| A | HOH539 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue NMM E 403 |
| Chain | Residue |
| E | PHE133 |
| E | THR184 |
| E | GLY185 |
| E | HIS187 |
| E | ASP189 |
| E | HIS273 |
| E | HOH523 |
| E | HOH558 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue NMM G 403 |
| Chain | Residue |
| G | PHE133 |
| G | GLY185 |
| G | HIS187 |
| G | ASP189 |
| G | HIS273 |
| G | HOH541 |
| G | HOH557 |
| G | HOH567 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue NMM H 403 |
| Chain | Residue |
| H | PHE133 |
| H | TRP174 |
| H | GLY185 |
| H | HIS187 |
| H | HOH513 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for Di-peptide HIS B 187 and ASP B 189 |
| Chain | Residue |
| B | GLY185 |
| B | ILE186 |
| B | ILE188 |
| B | PRO190 |
| B | ALA195 |
| B | TRP271 |
| B | TRP272 |
| B | HIS273 |
| B | HOH712 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1312 |
| Details | Domain: {"description":"JmjC","evidences":[{"source":"PROSITE-ProRule","id":"PRU00538","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 32 |
| Details | Motif: {"description":"Nuclear localization signal 1","evidences":[{"source":"PubMed","id":"14729065","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 32 |
| Details | Motif: {"description":"Nuclear localization signal 2","evidences":[{"source":"PubMed","id":"14729065","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 32 |
| Details | Motif: {"description":"Nuclear localization signal 3","evidences":[{"source":"PubMed","id":"14729065","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 24 |
| Details | Motif: {"description":"Nuclear localization signal 4","evidences":[{"source":"PubMed","id":"14729065","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 40 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20679243","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
