PDB: 1507 件ウェブページステータス検索Chemie searchBIRD

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1ZGU	Solution structure of the human Mms2-Ubiquitin complex 分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 variant 2 著者 Lewis, M.J, Saltibus, L.F, Hau, D.D, Xiao, W, Spyracopoulos, L. 登録日 2005-04-22 公開日 2006-04-04 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structural Basis for Non-Covalent Interaction Between Ubiquitin and the Ubiquitin Conjugating Enzyme Variant Human MMS2. J.Biomol.Nmr, 34, 2006
7A09	Structure of a human ABCE1-bound 43S pre-initiation complex - State III 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2020-08-07 公開日 2020-10-14 最終更新日 2021-01-13 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes. Embo J., 40, 2021
6S47	Saccharomyces cerevisiae 80S ribosome bound with ABCF protein New1 分子名称: 18S rRNA (1707-MER), 28S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Kasari, V, Pochopien, A.A, Margus, T, Murina, V, Turnbull, K, Zhou, Y, Nissan, T, Graf, M, Novacek, J, Atkinson, G.C, Johansson, M.J.O, Wilson, D.N, Hauryliuk, V. 登録日 2019-06-26 公開日 2019-07-24 最終更新日 2019-10-23 実験手法 ELECTRON MICROSCOPY (3.28 Å) 主引用文献 A role for the Saccharomyces cerevisiae ABCF protein New1 in translation termination/recycling. Nucleic Acids Res., 47, 2019
7ABI	Human pre-Bact-2 spliceosome 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Beta-catenin-like protein 1, ... 著者 Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. 登録日 2020-09-07 公開日 2021-02-10 実験手法 ELECTRON MICROSCOPY (8 Å) 主引用文献 Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
6S53	Crystal structure of TRIM21 RING domain in complex with an isopeptide-linked Ube2N~ubiquitin conjugate 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, E3 ubiquitin-protein ligase TRIM21, Polyubiquitin-C, ... 著者 Kiss, L, Boland, A, Neuhaus, D, James, L.C. 登録日 2019-06-30 公開日 2019-09-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases. Nat Commun, 10, 2019
7B5N	Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-UBE2L3~Ub~ARIH1. 分子名称: 5-azanylpentan-2-one, Cullin-1, E3 ubiquitin-protein ligase ARIH1, ... 著者 Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. 登録日 2020-12-05 公開日 2021-02-10 最終更新日 2021-03-10 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly. Nature, 590, 2021
7B5L	Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1 分子名称: 5-azanylpentan-2-one, Cullin-1, Cyclin-A2, ... 著者 Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. 登録日 2020-12-04 公開日 2021-02-10 最終更新日 2021-03-10 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly. Nature, 590, 2021
7B5M	Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-p27~Ub~ARIH1. Transition State 2 分子名称: Cullin-1, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, ... 著者 Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. 登録日 2020-12-05 公開日 2021-02-17 最終更新日 2021-03-10 実験手法 ELECTRON MICROSCOPY (3.91 Å) 主引用文献 Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly. Nature, 590, 2021
6SQO	Crystal structure of human MDM2 RING domain homodimer bound to UbcH5B-Ub 分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, NITRATE ION, ... 著者 Magnussen, H.M, Ahmed, S.F, Huang, D.T. 登録日 2019-09-04 公開日 2020-05-06 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain. Nat Commun, 11, 2020
7BHP	Cryo-EM structure of the human Ebp1 - 80S ribosome 分子名称: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Desogus, J, Bhaskar, V, Chao, J.A. 登録日 2021-01-11 公開日 2021-02-03 最終更新日 2021-03-31 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Dynamic association of human Ebp1 with the ribosome. Rna, 27, 2021
7BXG	MavC-UBE2N-Ub complex 分子名称: MavC, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N 著者 Gao, P, Wang, Y. 登録日 2020-04-19 公開日 2020-05-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.705 Å) 主引用文献 Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors. Nat Commun, 11, 2020
7BBD	Crystal structure of monoubiquitinated TRIM21 RING (Ub-RING) In complex with ubiquitin charged Ube2N (Ube2N~Ub) and Ube2V2 分子名称: Polyubiquitin-B,E3 ubiquitin-protein ligase TRIM21, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N, ... 著者 Kiss, L, Neuhaus, D, James, L.C. 登録日 2020-12-17 公開日 2021-01-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination. Nat Commun, 12, 2021
6SQS	Crystal structure of cat phospho-Ser429 MDM2 RING domain bound to UbcH5B-Ub 分子名称: E3 ubiquitin-protein ligase Mdm2, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 D2, ... 著者 Magnussen, H.M, Ahmed, S.F, Huang, D.T. 登録日 2019-09-04 公開日 2020-05-06 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain. Nat Commun, 11, 2020
7BBF	Crystal structure of ubiquitin charged Ube2N (Ube2N~Ub) in complex with Ube2V2 分子名称: Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2 著者 Kiss, L, Neuhaus, D, James, L.C. 登録日 2020-12-17 公開日 2021-01-27 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination. Nat Commun, 12, 2021
5K0Y	m48S late-stage initiation complex, purified from rabbit reticulocytes lysates, displaying eIF2 ternary complex and eIF3 i and g subunits relocated to the intersubunit face 分子名称: 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ... 著者 Simonetti, A, Brito Querido, J, Myasnikov, A.G, Mancera-Martinez, E, Renaud, A, Kuhn, L, Hashem, Y. 登録日 2016-05-17 公開日 2016-07-13 最終更新日 2018-04-18 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition. Mol.Cell, 63, 2016
5JUP	Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure II (mid-rotated 40S subunit) 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ... 著者 Abeyrathne, P, Koh, C.S, Grant, T, Grigorieff, N, Korostelev, A.A. 登録日 2016-05-10 公開日 2016-10-05 最終更新日 2019-11-27 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome. Elife, 5, 2016
5JUU	Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure V (least rotated 40S subunit) 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ... 著者 Abeyrathne, P, Koh, C.S, Grant, T, Grigorieff, N, Korostelev, A.A. 登録日 2016-05-10 公開日 2016-10-05 最終更新日 2019-11-27 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome. Elife, 5, 2016
7ABF	Human pre-Bact-1 spliceosome core structure 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. 登録日 2020-09-07 公開日 2020-12-09 最終更新日 2020-12-30 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
7ABG	Human pre-Bact-1 spliceosome 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cell division cycle 5-like protein, ... 著者 Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. 登録日 2020-09-07 公開日 2020-12-23 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (7.8 Å) 主引用文献 Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
6ZXE	Cryo-EM structure of a late human pre-40S ribosomal subunit - State F2 分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Ameismeier, M, Zemp, I, van den Heuvel, J, Thoms, M, Berninghausen, O, Kutay, U, Beckmann, R. 登録日 2020-07-29 公開日 2020-12-02 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural basis for the final steps of human 40S ribosome maturation. Nature, 587, 2020
7BWD	Structure of Dot1L-H2BK34ub Nucleosome Complex 分子名称: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... 著者 Lou, Z.Y, Liu, L, Cao, L, Ai, H.S, Sun, Z.X. 登録日 2020-04-14 公開日 2021-04-14 実験手法 ELECTRON MICROSCOPY (4.32 Å) 主引用文献 Structure of the Dot1L-H2BK34ub Nucleosome Complex Reveals an Unprecedented Crosstalk Activation Mechanism through Nucleosome Shape Distortion To Be Published
6ZON	SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 1 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2020-07-07 公開日 2020-07-29 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
6ZP4	SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 2 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2020-07-08 公開日 2020-07-29 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
5JUT	Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure IV (almost non-rotated 40S subunit) 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ... 著者 Abeyrathne, P, Koh, C.S, Grant, T, Grigorieff, N, Korostelev, A.A. 登録日 2016-05-10 公開日 2016-10-05 最終更新日 2019-11-27 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome. Elife, 5, 2016
6T7F	RCR E3 ligase E2-Ubiquitin transthiolation intermediate 分子名称: 3,3-bis(sulfanyl)-~{N}-(1~{H}-1,2,3-triazol-4-ylmethyl)propanamide, E3 ubiquitin-protein ligase MYCBP2, Polyubiquitin-C, ... 著者 Mabbitt, P.D, Virdee, S. 登録日 2019-10-21 公開日 2020-08-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity. Nat.Chem.Biol., 16, 2020

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