6SQS

Crystal structure of cat phospho-Ser429 MDM2 RING domain bound to UbcH5B-Ub

Summary for 6SQS

Entry DOI	10.2210/pdb6sqs/pdb
Related	6SQO 6SQP 6SQR
Descriptor	E3 ubiquitin-protein ligase Mdm2, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin-40S ribosomal protein S27a, ... (5 entities in total)
Functional Keywords	mdm2, mdmx, e3, e2, ubiquitin ligase, ubiquitin, phosphorylation, ligase
Biological source	Felis catus (Domestic cat) More
Total number of polymer chains	6
Total formula weight	65605.33
Authors	Magnussen, H.M.,Ahmed, S.F.,Huang, D.T. (deposition date: 2019-09-04, release date: 2020-05-06, Last modification date: 2024-01-24)
Primary citation	Magnussen, H.M.,Ahmed, S.F.,Sibbet, G.J.,Hristova, V.A.,Nomura, K.,Hock, A.K.,Archibald, L.J.,Jamieson, A.G.,Fushman, D.,Vousden, K.H.,Weissman, A.M.,Huang, D.T. Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain. Nat Commun, 11:2094-2094, 2020 Cited by PubMed: 32350255 DOI: 10.1038/s41467-020-15783-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.83 Å)

Structure validation